Di-anionic self-associating supramolecular amphiphiles (SSAs) as antimicrobial agents against MRSA and Escherichia coli

Herein, we report a series of di-anionic supramolecular self-associating amphiphiles (SSAs). We elucidate the antimicrobial properties of these SSAs against both methicillin resistant and . In addition, we show this class of compound to form both intra- and intermolecular hydrogen bonded macrocyclic...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2021-11, Vol.57 (89), p.11839-11842
Main Authors: White, Lisa J, Boles, Jessica E, Clifford, Melanie, Patenall, Bethany L, Hilton, Kira H L F, Ng, Kendrick K L, Ellaby, Rebecca J, Hind, Charlotte K, Mulvihill, Daniel P, Hiscock, Jennifer R
Format: Article
Language:English
Subjects:
Alkanesulfonates - chemistry
Alkanesulfonates - pharmacology
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Antiinfectives and antibacterials
Antimicrobial agents
E coli
Escherichia coli - drug effects
Hydrogen Bonding
Methicillin-Resistant Staphylococcus aureus - drug effects
Microbial Sensitivity Tests
Phenylurea Compounds - chemistry
Phenylurea Compounds - pharmacology
Proton Magnetic Resonance Spectroscopy
Surface-Active Agents - chemistry
Surface-Active Agents - pharmacology
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Summary:Herein, we report a series of di-anionic supramolecular self-associating amphiphiles (SSAs). We elucidate the antimicrobial properties of these SSAs against both methicillin resistant and . In addition, we show this class of compound to form both intra- and intermolecular hydrogen bonded macrocyclic structures in the solid state.
ISSN:1359-7345
1364-548X
DOI:10.1039/d1cc05455d