Use of hydroxychloroquine in dermatology: A multicenter retrospective study in Korea

Despite the expanding clinical application of hydroxychloroquine in dermatology, the overall data on hydroxychloroquine use among dermatologists are limited. With retrospective review of the medical records of the 790 patients who were prescribed hydroxychloroquine, we classified the diagnoses into...

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Bibliographic Details
Published in:Journal of dermatology 2022-01, Vol.49 (1), p.173-178
Main Authors: Lim, Jae Woo, Lee, June Hyunkyung, Kim, Hee Joo
Format: Article
Language:English
Subjects:
Cutaneous Lupus Erythematosus
Dermatology
Drug therapy
Humans
Hydroxychloroquine
Hydroxychloroquine - therapeutic use
Inflammation
Lichen planus
Lupus
lupus erythematosus
Lupus Erythematosus, Cutaneous - diagnosis
Lupus Erythematosus, Cutaneous - drug therapy
Lupus Erythematosus, Systemic
Medical records
Photodermatitis
prescription
real‐world experience
Republic of Korea
Retrospective Studies
Skin diseases
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Summary:Despite the expanding clinical application of hydroxychloroquine in dermatology, the overall data on hydroxychloroquine use among dermatologists are limited. With retrospective review of the medical records of the 790 patients who were prescribed hydroxychloroquine, we classified the diagnoses into 12 disease categories, the lupus erythematosus group being the largest. The lupus erythematosus group had the longest prescription duration (median, 6.2 months), whereas the photodermatitis group had a significantly shorter prescription duration (median, 0.5 months). The overall good response rate was 77.1%. The photodermatitis group had the best response (88.7%), followed by the lupus panniculitis (85.1%) and lichen planus (84.4%). In conclusion, hydroxychloroquine has proven utility for various inflammatory skin diseases, including but not limited to cutaneous lupus erythematosus.
ISSN:0385-2407
1346-8138
DOI:10.1111/1346-8138.16200