Implications of Mycoplasma hemofelis Bacterial Load on the Hematological Parameters of Naturally Infected Cats

Mycoplasma hemofelis is the most pathogenic hemoplasma species that affect cats. M. hemofelis may cause an acute infection that leads to hemolytic anaemia. The objective of this study was to detect and to quantify the load of M. hemofelis in cats by conventional polymerase chain reaction (PCR) and b...

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Bibliographic Details
Published in:Topics in companion animal medicine 2022-03, Vol.47, p.100611-100611, Article 100611
Main Authors: Guerra, Thais Rodrigues, Otsubo, Amanda Atsumy Funakawa, de Paula, Daphine Ariadne Jesus, Pereira, Mariana Elisa, Sousa, Valéria Régia Franco, Dutra, Valéria, de Almeida, Arleana do Bom Parto Ferreira
Format: Article
Language:English
Subjects:
Anemia
Animals
Bacteria
Bacterial Load - veterinary
Blood
cat
Cat Diseases
Cats
Confidence intervals
DNA polymerase
DNA, Bacterial
Female
Hematology
Hemolytic anemia
hemoplasm
Infections
Male
Mycoplasma
Mycoplasma - genetics
Mycoplasma hemofelis
Mycoplasma Infections - microbiology
Mycoplasma Infections - veterinary
Parameters
Polymerase chain reaction
Polymerase Chain Reaction - veterinary
qPCR
Statistical analysis
Citations: Items that this one cites
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Summary:Mycoplasma hemofelis is the most pathogenic hemoplasma species that affect cats. M. hemofelis may cause an acute infection that leads to hemolytic anaemia. The objective of this study was to detect and to quantify the load of M. hemofelis in cats by conventional polymerase chain reaction (PCR) and by quantitative PCR (qPCR) and to describe the possible hematological changes. M. hemofelis DNA was detected in 28.6% of the randomly selected cats (42 of 147) attended at the Veterinary Hospital of the Federal University of Mato Grosso, Brazil. The agreement between conventional PCR and qPCR was substantive (k 0.6). Females were twice as likely to acquire infection as males (odds ratio, 2.31). There was no statistically significant association (P > .05) and little/no correlation between the hematological parameters and the average of bacterial load. The results indicate that M. hemofelis infection is not related to clinical signs and bacterial blood load in cats. The agreement between conventional and quantitative PCR made it possible to detect infection by M. hemofelis in a larger number of cats.
ISSN:1938-9736
1946-9837
1876-7613
DOI:10.1016/j.tcam.2021.100611