Prognostic Factors of Potential Early Recurrence of Hypopharyngeal Carcinoma

Background/Aim: Prognostic factors of hypopharyngeal carcinoma have been reported previously. However, recurrent cases of this disease occurring within 6 months of treatment have been excluded or poorly documented in many studies. We aimed to evaluate the prognostic factors of hypopharyngeal carcino...

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Bibliographic Details
Published in:Anticancer research 2021-11, Vol.41 (11), p.5761-5766
Main Authors: Baba, Daisuke, Fushimi, Chihiro, Hanyu, Kenji, Masubuchi, Tatsuo, Tada, Yuichiro, Mura, Koki
Format: Article
Language:English
Subjects:
Cancer
Evaluation
Health services
Patients
Physicians
Statistical analysis
Throat cancer
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Summary:Background/Aim: Prognostic factors of hypopharyngeal carcinoma have been reported previously. However, recurrent cases of this disease occurring within 6 months of treatment have been excluded or poorly documented in many studies. We aimed to evaluate the prognostic factors of hypopharyngeal carcinoma recurrence within 6 months. Patients and Methods: A total of 120 patients were eligible for this retrospective study. Recurrent cases of hypopharyngeal carcinoma occurring within 6 months of treatment were evaluated and compared with non-recurrent cases. Results: Recurrence within 6 months was detected in 28/50 cases. In univariate analyses, classification markers (pT≥4a and cN≥2b) were statistically significant prognostic factors for early recurrence (p=0.04 and p=0.04, respectively); however, only pT≥4a was predictive of recurrence in multivariate analyses (p=0.02). Conclusion: Risk stratification according to the prognostic factor pT≥4a will allow physicians to identify patients who should be followed meticulously within the first 6 months.
ISSN:0250-7005
1791-7530
DOI:10.21873/anticanres.15392