Differences in standardized neonatal encephalopathy exam criteria may impact therapeutic hypothermia eligibility

Background Therapeutic hypothermia (TH) is routinely provided to those with moderate or severe neonatal encephalopathy (NE). Subtle differences exist in the standardized exams used to define NE severity. We aimed to assess if an infant’s TH eligibility status differed if they were evaluated using ei...

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Bibliographic Details
Published in:Pediatric research 2022-09, Vol.92 (3), p.791-798
Main Authors: Walsh, Brian H., El-Shibiny, Hoda, Munster, Chelsea, Yang, Edward, Inder, Terrie E., El-Dib, Mohamed
Format: Article
Language:English
Subjects:
Clinical Research Article
Hypothermia
Medicine
Medicine & Public Health
Pediatric Surgery
Pediatrics
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Summary:Background Therapeutic hypothermia (TH) is routinely provided to those with moderate or severe neonatal encephalopathy (NE). Subtle differences exist in the standardized exams used to define NE severity. We aimed to assess if an infant’s TH eligibility status differed if they were evaluated using either the NICHD/Neonatal Research Network’s (NICHD-NRN) or TOBY/British Association of Perinatal Medicine’s (TOBY-BAPM) neurological exam. Methods Encephalopathic infants ≥36 weeks with evidence of perinatal asphyxia and complete documentation of the neurological exam
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-021-01834-7