A disintegrin and metalloproteinase 12 (ADAM12) is reduced at 36 weeks’ gestation in pregnancies destined to deliver small for gestational age infants

First trimester circulating ADAM12 is reduced in fetal growth restriction (FGR) and preeclampsia. We measured plasma ADAM12 at 36 weeks’ gestation preceding diagnosis of term preeclampsia or delivery of a small for gestational age (SGA; birthweight

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Bibliographic Details
Published in:Placenta (Eastbourne) 2022-01, Vol.117, p.1-4
Main Authors: Andres, Faith, Wong, Georgia P., Walker, Susan P., MacDonald, Teresa M., Keenan, Emerson, Cannon, Ping, Nguyen, Tuong-Vi, Hannan, Natalie J., Tong, Stephen, Kaitu'u-Lino, Tu'uhevaha J.
Format: Article
Language:English
Subjects:
ADAM12
ADAM12 Protein - blood
Biomarker
Biomarkers - blood
Female
FGR
Humans
Infant, Newborn
Infant, Small for Gestational Age
Pre-Eclampsia - blood
Preeclampsia
Pregnancy
Prospective Studies
SGA
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Description
Summary:First trimester circulating ADAM12 is reduced in fetal growth restriction (FGR) and preeclampsia. We measured plasma ADAM12 at 36 weeks’ gestation preceding diagnosis of term preeclampsia or delivery of a small for gestational age (SGA; birthweight
ISSN:0143-4004
1532-3102
DOI:10.1016/j.placenta.2021.11.001