Risk of Cancer in Paediatric onset Inflammatory Bowel Diseases: A Nation-wide Study From the epi-IIRN

Abstract Background Paediatric onset IBD [PIBD] is characterised by a more extensive phenotype than adult-onset IBD and a higher utilisation of immunosuppressive medications; both may be associated with malignancy. We aimed to assess the risk of cancer in a nationwide cohort of PIBD and to explore t...

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Published in:Journal of Crohn's and colitis 2022-06, Vol.16 (5), p.786-795
Main Authors: Atia, Ohad, Harel, Sasha, Ledderman, Natan, Greenfeld, Shira, Kariv, Revital, Dotan, Iris, Balicer, Ran, Silverman, Barbara, Matz, Eran, Levi, Zohar, Waterman, Matti, Fried, Iris, Rowe, Jacob M, Turner, Dan
Format: Article
Language:English
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Summary:Abstract Background Paediatric onset IBD [PIBD] is characterised by a more extensive phenotype than adult-onset IBD and a higher utilisation of immunosuppressive medications; both may be associated with malignancy. We aimed to assess the risk of cancer in a nationwide cohort of PIBD and to explore the risks associated with medical treatments. Methods PIBD patients [
ISSN:1873-9946
1876-4479
DOI:10.1093/ecco-jcc/jjab205