Comparison between various biosensor methods for human T-lymphotropic virus-1 (HTLV-1) detection

Due to the drawback of traditional and current diagnostic methods including serological and molecular assays, the development of the rapid and free-PCR techniques can be an alternative technique for the human T-cell lymphotropic virus (HTLV-1) DNA detection sequences. On the other hand, early detect...

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Bibliographic Details
Published in:Molecular biology reports 2022-02, Vol.49 (2), p.1513-1517
Main Authors: Kamali, Peyman, Zandi, Milad, Ghasemzadeh-Moghaddam, Hamed, Fani, Mona
Format: Article
Language:English
Subjects:
Animal Anatomy
Animal Biochemistry
Base Sequence - genetics
Biomedical and Life Sciences
Biosensing Techniques - methods
Biosensors
Central nervous system diseases
DNA viruses
Histology
HTLV-I Infections - diagnosis
HTLV-I Infections - genetics
Human T-lymphotropic virus 1 - genetics
Human T-lymphotropic virus 1 - pathogenicity
Humans
Infectious diseases
Leukemia-Lymphoma, Adult T-Cell - genetics
Leukemia-Lymphoma, Adult T-Cell - pathology
Leukemia-Lymphoma, Adult T-Cell - virology
Life Sciences
Lymphocytes T
Lymphoma
Morphology
Nucleotide sequence
Paraparesis, Tropical Spastic - virology
Polymerase Chain Reaction - methods
Review
Spastic paraparesis
Spinal cord
Tropical spastic paraparesis
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Summary:Due to the drawback of traditional and current diagnostic methods including serological and molecular assays, the development of the rapid and free-PCR techniques can be an alternative technique for the human T-cell lymphotropic virus (HTLV-1) DNA detection sequences. On the other hand, early detection of HTLV-1 prevents two dangerous diseases including Adult T-cell leukemia/lymphoma and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis. The biosensor-based methods are sensitive techniques that can provide new opportunities to detect infectious diseases, particularly in the early stage. This study provides a comparative view among recently designed biosensors for the detection of HTLV-1.
ISSN:0301-4851
1573-4978
DOI:10.1007/s11033-021-06959-w