Rates of Herpes Simplex Virus Types 1 and 2 in Ocular and Peri-ocular Specimens

To evaluate the rates of Herpes Simplex Virus types 1 (HSV-1) and 2 (HSV-2) in ocular specimens. Retrospective case series of all patients with a positive laboratory evaluation for ocular HSV performed at the Auckland District Health Board, Auckland, New Zealand between 1 January 2006 and 31 Decembe...

Full description

Saved in:
Bibliographic Details
Published in:Ocular immunology and inflammation 2023-01, Vol.31 (1), p.149-152
Main Author: Meyer, Jay J.
Format: Article
Language:English
Subjects:
acute retinal necrosis
blepharitis
conjunctivitis
Eye
Herpes Simplex - diagnosis
Herpes Simplex - epidemiology
Herpes simplex keratitis
Herpesvirus 1, Human - genetics
Herpesvirus 2, Human - genetics
Humans
keratitis
Keratitis, Herpetic - diagnosis
Keratitis, Herpetic - epidemiology
Retrospective Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To evaluate the rates of Herpes Simplex Virus types 1 (HSV-1) and 2 (HSV-2) in ocular specimens. Retrospective case series of all patients with a positive laboratory evaluation for ocular HSV performed at the Auckland District Health Board, Auckland, New Zealand between 1 January 2006 and 31 December 2017 were included in the study. A total of 423 specimens were positive for HSV-1 (99.3%, n = 419) or HSV-2 (0.7%; n = 4). The majority of positive tests were identified through DNA amplification (n = 352; 83%) testing while the remainder were obtained by viral culture (n = 71; 17%). Ocular disease caused by HSV-2 in this study included acute retinal necrosis (n = 2), keratitis (n = 1), and blepharitis (n = 1). HSV type 2 is a rare cause of ocular and peri-ocular infection but may cause severe, vision threatening disease.
ISSN:0927-3948
1744-5078
DOI:10.1080/09273948.2021.1998548