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Value of spectral detector computed tomography to differentiate infected from noninfected thoracoabominal fluid collections

To investigate the diagnostic value of spectral detector CT (SDCT)-derived virtual non-contrast (VNC), virtual monoenergetic images (VMI) and iodine overlays (IO) for distinguishing infected from noninfected fluid collections (FC) in the chest or abdomen. This retrospective study included 58 patient...

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Bibliographic Details
Published in:European journal of radiology 2021-12, Vol.145, p.110037-110037, Article 110037
Main Authors: Reimer, Robert Peter, Gertz, Roman Johannes, Pennig, Lenhard, Henze, Jörn, Celik, Erkan, Lennartz, Simon, Maintz, David, Zopfs, David, Große Hokamp, Nils
Format: Article
Language:English
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Summary:To investigate the diagnostic value of spectral detector CT (SDCT)-derived virtual non-contrast (VNC), virtual monoenergetic images (VMI) and iodine overlays (IO) for distinguishing infected from noninfected fluid collections (FC) in the chest or abdomen. This retrospective study included 58 patients with venous phase SDCT with 77 FC. For all included FC, microbiological analysis of aspirated fluid served as reference. For quantitative analysis, wall thickness was measured, and (ROI)-based analysis performed within the fluid, the FC’s wall (if any) and the aorta. Two radiologists qualitatively evaluated visibility of wall enhancement, diagnostic confidence regarding infection of fluid collection, confidence of CT-guided drainage catheter placement and visibility of anatomical landmarks in conventional images (CI) and VNC, VMI40keV, IO. Wall thickness significantly differed between infected (n = 46) and noninfected (n = 31) FC (3.5 ± 1.8 mm vs. 1.4 ± 1.8 mm, AUC = 0.81; p 
ISSN:0720-048X
1872-7727
DOI:10.1016/j.ejrad.2021.110037