Influence of diabetes mellitus interactions with cardiovascular risk factors on post-myocardial infarction heart failure hospitalizations

There is a paucity of information regarding how cardiovascular risk factors (RF) modulate the impact of diabetes mellitus (DM) on the heart failure hospitalization (HFH) risk following an acute myocardial infarction (AMI). Adult survivors of an AMI were retrospectively identified from the 2014 US Na...

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Published in:International journal of cardiology 2022-02, Vol.348, p.140-146
Main Authors: Yandrapalli, Srikanth, Malik, Aaqib H., Namrata, Fnu, Pemmasani, Gayatri, Bandyopadhyay, Dhrubajyoti, Vallabhajosyula, Saraschandra, Aronow, Wilbert S., Frishman, William H., Jain, Diwakar, Cooper, Howard A., Panza, Julio A.
Format: Article
Language:English
Subjects:
Acute myocardial infarction
Adult
Cardiovascular Diseases
Diabetes mellitus
Diabetes Mellitus - diagnosis
Diabetes Mellitus - epidemiology
Heart Disease Risk Factors
Heart failure
Heart Failure - diagnosis
Heart Failure - epidemiology
Hospitalization
Humans
Myocardial Infarction - diagnosis
Myocardial Infarction - epidemiology
Outcomes
Retrospective Studies
Risk Factors
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Summary:There is a paucity of information regarding how cardiovascular risk factors (RF) modulate the impact of diabetes mellitus (DM) on the heart failure hospitalization (HFH) risk following an acute myocardial infarction (AMI). Adult survivors of an AMI were retrospectively identified from the 2014 US Nationwide Readmissions Database. The impact of DM on the risk for a 6-month HFH was studied in subgroups of RFs using multivariable logistic regression to adjust for baseline risk differences. Individual interactions of DM with RFs were tested. Of 237,549 AMI survivors, 37.2% patients had DM. Primary outcome occurred in 12,934 patients (5.4%), at a 106% higher rate in DM patients (7.9% vs 4.0%, p 
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2021.11.086