Oesophageal atresia with very low birth weight: Clinical characteristics and long-term outcome

• Published in: Journal of pediatric surgery 2022-02, Vol.57 (2), p.192-194
• Main Authors: Koivusalo, Antti I, Suominen, Janne S, Pakarinen, Mikko P
• Format: Article
• Language: English
• Subjects: Anastomosis, Surgical; Anastomotic Leak; Birth Weight; Chromosomal anomalies; Esophageal Atresia - epidemiology; Esophageal Atresia - surgery; Esophagoplasty; Humans; Infant, Newborn; Infant, Very Low Birth Weight; Ooesophageal atresia; Retrospective Studies; Very low birth weight
• ISSN: 0022-3468; 1531-5037
• DOI: 10.1016/j.jpedsurg.2021.10.047

•10% of patients with oesophageal atresia (OA) have very low birth weight VLBW.•the occurrence of OA patients with VLBW is not decreasing.•VLBW patients´rates of survival and final repair of OA have markedly increased during 20 years.•delayed repair may benefit outcome in VLBW patients. An assessment of the clinical data and outcome of patients with oesophageal atresia (OA) with very low birth weight (VLBW) was completed. With ethical consent, we reviewed the records of 327 successive patients with OA from 1980 to 2020. Main outcome measures survival and oesophageal repair were compared between patients with VLBW(≤1500 g) and with BW>1500 g. Thirty-four (10%) patients had VLBW. Gross types of OA in VLBW were similar as in other patients: A (15%/7%), B (3%/3%), C (78%/82%), D (3%/4%), E (0%/7%), F (0%/1%) (p = 0.16–0.99). In VLBW the incidence of congenital heart disease (CHD) (47%) and trisomy 13/18 and Cri du Chat (15%) were higher than in BW>1500 g (23% and 1%), (p = 0.001 both). In VLBW one-month mortality was 35% vs 4% in patients with BW>1500 g (p