Hypochloraemia following admission to hospital with heart failure is common and associated with an increased risk of readmission or death: a report from OPERA-HF

Hypochloraemia is common in patients hospitalized with heart failure (HF) and associated with a high risk of adverse outcomes during admission and following discharge. We assessed the significance of changes in serum chloride concentrations in relation to serum sodium and bicarbonate concentrations...

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Bibliographic Details
Published in:European heart journal. Acute cardiovascular care 2022-01, Vol.11 (1), p.43-52
Main Authors: Cuthbert, J J, Brown, O I, Urbinati, A, Pan, D, Pellicori, P, Dobbs, K, Bulemfu, J, Kazmi, S, Sokoreli, I, Pauws, S C, Riistama, J M, Cleland, J G F, Clark, A L
Format: Article
Language:English
Subjects:
Heart Failure - complications
Heart Failure - epidemiology
Hospitalization
Hospitals
Humans
Hyponatremia - epidemiology
Hyponatremia - etiology
Patient Readmission
Prognosis
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Summary:Hypochloraemia is common in patients hospitalized with heart failure (HF) and associated with a high risk of adverse outcomes during admission and following discharge. We assessed the significance of changes in serum chloride concentrations in relation to serum sodium and bicarbonate concentrations during admission in a cohort of 1002 consecutive patients admitted with HF and enrolled into an observational study based at a single tertiary centre in the UK. Hypochloraemia (
ISSN:2048-8726
2048-8734
DOI:10.1093/ehjacc/zuab097