A Rare Case of Low-Grade Dedifferentiated Liposarcoma Presenting as a Pharyngeal Polyp: Avoiding a Pitfall With Significant Repercussions

Dedifferentiated liposarcoma is a nonlipogenic sarcoma of variable histological grade that frequently arises in association with a well-differentiated liposarcoma. Dedifferentiation occurs in approximately 10% of well-differentiated liposarcomas and is most commonly encountered in the retroperitoneu...

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Bibliographic Details
Published in:International journal of surgical pathology 2022-06, Vol.30 (4), p.405-412
Main Authors: Georgantzoglou, Natalia, Green, Donald, Lefferts, Joel A., Giannikaki, Linda, Chliara, Eudoxia, Stavrianaki, Anna, Kerr, Darcy A., Linos, Konstantinos
Format: Article
Language:English
Subjects:
Humans
Lipoma - pathology
Liposarcoma
Liposarcoma - diagnosis
Liposarcoma - pathology
Liposarcoma - surgery
Pharynx - pathology
Polyps - pathology
Soft Tissue Neoplasms - pathology
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Summary:Dedifferentiated liposarcoma is a nonlipogenic sarcoma of variable histological grade that frequently arises in association with a well-differentiated liposarcoma. Dedifferentiation occurs in approximately 10% of well-differentiated liposarcomas and is most commonly encountered in the retroperitoneum. Dedifferentiated liposarcoma of the upper respiratory tract is an extremely rare occurrence. Herein, we report a very rare case of low-grade dedifferentiated liposarcoma of the pharynx that presented as a polyp mimicking a benign process clinically and microscopically. We discuss the relevant molecular findings and review the current literature.
ISSN:1066-8969
1940-2465
DOI:10.1177/10668969211062859