Dehydro-thermally cross-linked collagen-poly(vinyl alcohol) blends: mechanical, biological and surface properties

The mechanical, biological, and surface properties of films, based on blends of soluble collagen and poly(vinyl alcohol), were investigated. Films prepared by casting were cross-linked by a dehydro-thermal treatment. The mechanical behavior of the materials was studied by dynamic-mechanical thermal...

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Bibliographic Details
Published in:Journal of materials science. Materials in medicine 1996-05, Vol.7 (5), p.297-300
Main Authors: Cascone, M. G., Lazzeri, L., Barbani, N., Polacco, G., Pollicino, A., Giusti, P.
Format: Article
Language:English
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Summary:The mechanical, biological, and surface properties of films, based on blends of soluble collagen and poly(vinyl alcohol), were investigated. Films prepared by casting were cross-linked by a dehydro-thermal treatment. The mechanical behavior of the materials was studied by dynamic-mechanical thermal analysis. The biological properties of the films were evaluated by performing cytotoxicity and cytocompatibility in vitro tests. Surface characterization was carried out by X-ray electron spectroscopy. The results obtained indicate that these materials behave as two-phase systems, and a remarkable enrichment of collagen in the surface with respect to the bulk was observed. Cytocompatibility tests show that the blending of the two polymers creates a better substrate for cell growth in comparison with pure components. (Author)
ISSN:0957-4530
1573-4838
DOI:10.1007/BF00058570