Chronic kidney disease after adrenalectomy in a patient with primary aldosteronism

We report one case of estimated glomerular filtration rate (eGFR) decline after taking unilateral adrenalectomy due to aldosterone adenoma. A 60-year-old male with 23-year history of hypertension was reported to the endocrinologist due to hypokalemia (serum potassium 3.01 mmol/L). Urine microalbumin...

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Bibliographic Details
Published in:Beijing da xue xue bao. Journal of Peking University. Yi xue ban 2021-12, Vol.53 (6), p.1201-1204
Main Authors: An, W C, Yan, H X, Deng, Z Z, Chen, F, Ou, X H, Jin, H X, Huang, W
Format: Article
Language:Chinese
Subjects:
Adrenal Gland Neoplasms - surgery
Adrenalectomy
Glomerular Filtration Rate
Humans
Hyperaldosteronism - etiology
Hyperaldosteronism - surgery
Male
Middle Aged
Renal Insufficiency, Chronic
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Summary:We report one case of estimated glomerular filtration rate (eGFR) decline after taking unilateral adrenalectomy due to aldosterone adenoma. A 60-year-old male with 23-year history of hypertension was reported to the endocrinologist due to hypokalemia (serum potassium 3.01 mmol/L). Urine microalbumin/creatinine (ALB/CR) was 70.15 mg/g, serum creatinine was 82 μmol/L and eGFR was 89.79 mL/(min·1.73 m ). Random serum aldosterone was 172.2-203.5 ng/L, and random plasma rennin activity was 0-0.17 μg/(L·h). His captopril challenge test suggested that his aldosterone le-vels were suppressed by 8% (< 30%) and the adrenal enhanced computed tomography scan revealed a left adrenal tumor. The patient was diagnosed with primary hyperaldosteronism (PA), aldosterone adenoma and underwent left laparoscopic adrenalectomy. Histological examination confirmed adrenal cortical adenoma. One week after the operation, his serum creatinine was increased to 127 μmol/L compared with preoperative level; eGFR was 32.34 mL/(min·1.73 m ).
ISSN:1671-167X