Clinical characteristics of central nervous system involvement in IgG4 related diseases

To improve the understanding of the clinical characteristics of immunoglobulin G4-related disease (IgG4-RD) with central nervous system (CNS) involvement, so as to contribute to the early diagnosis and treatment. In this study, 10 patients with IgG4-RD with CNS involvement were selected. Clinical da...

Full description

Saved in:
Bibliographic Details
Published in:Beijing da xue xue bao. Journal of Peking University. Yi xue ban 2021-12, Vol.53 (6), p.1043-1048
Main Authors: Meng, G Y, Zhang, Y X, Liu, Y Y
Format: Article
Language:Chinese
Subjects:
Humans
Immunoglobulin G
Immunoglobulin G4-Related Disease
Inflammation
Pituitary Gland
Retrospective Studies
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To improve the understanding of the clinical characteristics of immunoglobulin G4-related disease (IgG4-RD) with central nervous system (CNS) involvement, so as to contribute to the early diagnosis and treatment. In this study, 10 patients with IgG4-RD with CNS involvement were selected. Clinical data including demographic features, clinical manifestations, organ involvement, laboratory findings, radiological results, pathology, treatments and outcomes were collected retrospectively. Among the 10 IgG4-RD patients complicated with CNS involvement, 6 cases manifested as pituitary involvement and 4 cases manifested as dural involvement. Only 2 patients had nervous system involvement alone, while the left patients were complicated with other organ involvement besides nervous system. Half of the patients presented nervous system involvement as the initial manifestation, and the main symptoms of nervous system included polydipsia, polyuria, headache, decreased vision and so on. In the laboratory examination, the se
ISSN:1671-167X