Lower levels of low-density lipoprotein cholesterol are associated with a lower prevalence of thin-cap fibroatheroma in statin-treated patients with coronary artery disease

•Lower LDL-C levels with statins were associated with a lower prevalence of TCFAs.•A correlation between LDL-C and TCFAs was observed in patients with lower HbA1c.•LDL-C levels

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Bibliographic Details
Published in:Journal of clinical lipidology 2022-01, Vol.16 (1), p.104-111
Main Authors: Hashimoto, Takuya, Minami, Yoshiyasu, Asakura, Kiyoshi, Katamine, Masahiro, Kato, Ayami, Katsura, Aritomo, Sato, Toshimitsu, Muramatsu, Yusuke, Kameda, Ryo, Meguro, Kentaro, Shimohama, Takao, Ako, Junya
Format: Article
Language:English
Subjects:
Atherosclerosis - pathology
Cholesterol, LDL
Coronary Artery Disease - complications
Coronary Artery Disease - drug therapy
Coronary Artery Disease - epidemiology
Coronary Vessels - diagnostic imaging
Coronary Vessels - pathology
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Lipid-lowering therapy
Optical coherence tomography
Percutaneous coronary intervention
Plaque, Atherosclerotic - complications
Plaque, Atherosclerotic - diagnostic imaging
Plaque, Atherosclerotic - drug therapy
Prevalence
Secondary prevention
Vulnerable plaque
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Description
Summary:•Lower LDL-C levels with statins were associated with a lower prevalence of TCFAs.•A correlation between LDL-C and TCFAs was observed in patients with lower HbA1c.•LDL-C levels
ISSN:1933-2874
1876-4789
DOI:10.1016/j.jacl.2021.11.012