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CYP2C8-Mediated Formation of a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Cytochrome P450 and Aldehyde Oxidase Substrate

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Bibliographic Details
Published in:Drug metabolism and disposition 2022-03, Vol.50 (3), p.235-242
Main Authors: Asano, Daigo, Hamaue, Syoya, Zahir, Hamim, Shiozawa, Hideyuki, Nishiya, Yumi, Kimura, Takako, Kazui, Miho, Yamamura, Naotoshi, Ikeguchi, Marie, Shibayama, Takahiro, Inoue, Shin-Ichi, Shinozuka, Tsuyoshi, Watanabe, Toshiyuki, Yahara, Chizuko, Watanabe, Nobuaki, Yoshinari, Kouichi
Format: Article
Language:English
Online Access:Get full text
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ISSN:1521-009X
DOI:10.1124/dmd.121.000665