Triglyceride glucose index reflects the unfavorable changes of left ventricular diastolic functions and structure in uncomplicated newly diagnosed hypertensive patients

Left ventricular (LV) diastolic dysfunction and structural abnormalities are common cardiac changes in hypertension (HTN), and several factors other than high blood pressure (BP) may play a role in these changes. The aim of this study was to reveal the relationship between triglyceride glucose (TyG)...

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Bibliographic Details
Published in:Clinical and experimental hypertension (1993) 2022-04, Vol.44 (3), p.215-222
Main Authors: Cetin Sanlialp, Sara, Sanlialp, Musa, Nar, Gokay, Malcok, Aydan
Format: Article
Language:English
Subjects:
Diastole - physiology
diastolic function
Glucose
Humans
Hypertension
Hypertension - diagnosis
Hypertension - diagnostic imaging
Hypertrophy, Left Ventricular - diagnostic imaging
insulin resistance
left ventricular structure
triglyceride glucose index
Triglycerides
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Summary:Left ventricular (LV) diastolic dysfunction and structural abnormalities are common cardiac changes in hypertension (HTN), and several factors other than high blood pressure (BP) may play a role in these changes. The aim of this study was to reveal the relationship between triglyceride glucose (TyG) index, a novel parameter for insulin resistance (IR), with LV diastolic function and structure in hypertensive patients. A total of 119 newly diagnosed, untrated hypertensive patients free of diabetes and/or cardiovascular complications were included in this study. IR was estimated with the TyG index calculated from ln [fasting TG (mg/dL) × fasting blood glucose (mg/dL)/2]. Two-dimensional and Doppler echocardiographic examinations were performed to assess LV diastolic functions and structure. Based on median TyG index, 51 patients was assigned as group I (8.7). In patients with high TyG index, left atrial volume index (LAVi) (p
ISSN:1064-1963
1525-6006
DOI:10.1080/10641963.2021.2018599