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Antibacterial sesquiterpenoids from Solanum lyratum
Investigation into the chemical diversity of led to the discovery of one new sesquiterpenoid, solyraterpenoid A ( ), and two known compounds ( and ). The structure incorporating absolute configuration of was determined via spectroscopic data, mainly including HRESIMS and NMR, and single-crystal X-ra...
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Published in: | Natural product research 2022-11, Vol.36 (22), p.1-5867 |
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container_issue | 22 |
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container_title | Natural product research |
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creator | Liang, Jun Liang, Wenbin Chen, Xintao Wang, Qibin |
description | Investigation into the chemical diversity of
led to the discovery of one new sesquiterpenoid, solyraterpenoid A (
), and two known compounds (
and
). The structure incorporating absolute configuration of
was determined via spectroscopic data, mainly including HRESIMS and NMR, and single-crystal X-ray diffraction analysis. Compound
showed significant antibacterial activity against
,
, and
with MIC values of 8, 8, and 4
g/mL, respectively. |
doi_str_mv | 10.1080/14786419.2021.2019734 |
format | article |
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led to the discovery of one new sesquiterpenoid, solyraterpenoid A (
), and two known compounds (
and
). The structure incorporating absolute configuration of
was determined via spectroscopic data, mainly including HRESIMS and NMR, and single-crystal X-ray diffraction analysis. Compound
showed significant antibacterial activity against
,
, and
with MIC values of 8, 8, and 4
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led to the discovery of one new sesquiterpenoid, solyraterpenoid A (
), and two known compounds (
and
). The structure incorporating absolute configuration of
was determined via spectroscopic data, mainly including HRESIMS and NMR, and single-crystal X-ray diffraction analysis. Compound
showed significant antibacterial activity against
,
, and
with MIC values of 8, 8, and 4
g/mL, respectively.</description><subject>Absolute configuration</subject><subject>Antibacterial activity</subject><subject>E coli</subject><subject>Klebsiella</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Pseudomonas aeruginosa</subject><subject>Sesquiterpenoids</subject><subject>Single crystals</subject><subject>Solanum lyratum</subject><subject>X-ray diffraction</subject><issn>1478-6419</issn><issn>1478-6427</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNpdkMtKAzEUhoMotlYfQRlw42ZqbpNklqXUCxRcqOuQZBKYMjNpk8mib29KLws3OTmH7xx-PgAeEZwjKOArolwwiuo5hhjlB9Wc0CswPcxLRjG_vvxRPQF3MW5gJququgUTQmtGiMBTQBbD2GplRhta1RXRxl1qc7O1g2-bWLjg--Lbd2pIfdHtgxpTfw9unOqifTjVGfh9W_0sP8r11_vncrEuDRF0LFmVUznTECWYY8pSjY2utWmEFo1zXFeOaSYE1UhRBw2xmsOKQN1YbhXXZAZejne3we-SjaPs22hsl8NYn6LEDGWcoFpk9PkfuvEpDDmdxJwIVkOEYKaqI2WCjzFYJ7eh7VXYSwTlwao8W5UHq_JkNe89na4n3dvmsnXWSP4Ax-pylA</recordid><startdate>20221117</startdate><enddate>20221117</enddate><creator>Liang, Jun</creator><creator>Liang, Wenbin</creator><creator>Chen, Xintao</creator><creator>Wang, Qibin</creator><general>Taylor & Francis Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QO</scope><scope>7QP</scope><scope>7QR</scope><scope>7T7</scope><scope>7TK</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20221117</creationdate><title>Antibacterial sesquiterpenoids from Solanum lyratum</title><author>Liang, Jun ; Liang, Wenbin ; Chen, Xintao ; Wang, Qibin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-65201fcd3a86f6ae4b2cb9bcd8b8dff7b5f6b6884b1a4f0c3eb70530bde7ea7b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Absolute configuration</topic><topic>Antibacterial activity</topic><topic>E coli</topic><topic>Klebsiella</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Pseudomonas aeruginosa</topic><topic>Sesquiterpenoids</topic><topic>Single crystals</topic><topic>Solanum lyratum</topic><topic>X-ray diffraction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liang, Jun</creatorcontrib><creatorcontrib>Liang, Wenbin</creatorcontrib><creatorcontrib>Chen, Xintao</creatorcontrib><creatorcontrib>Wang, Qibin</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Natural product research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liang, Jun</au><au>Liang, Wenbin</au><au>Chen, Xintao</au><au>Wang, Qibin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibacterial sesquiterpenoids from Solanum lyratum</atitle><jtitle>Natural product research</jtitle><addtitle>Nat Prod Res</addtitle><date>2022-11-17</date><risdate>2022</risdate><volume>36</volume><issue>22</issue><spage>1</spage><epage>5867</epage><pages>1-5867</pages><issn>1478-6419</issn><eissn>1478-6427</eissn><abstract>Investigation into the chemical diversity of
led to the discovery of one new sesquiterpenoid, solyraterpenoid A (
), and two known compounds (
and
). The structure incorporating absolute configuration of
was determined via spectroscopic data, mainly including HRESIMS and NMR, and single-crystal X-ray diffraction analysis. Compound
showed significant antibacterial activity against
,
, and
with MIC values of 8, 8, and 4
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source | Taylor and Francis Science and Technology Collection |
subjects | Absolute configuration Antibacterial activity E coli Klebsiella NMR Nuclear magnetic resonance Pseudomonas aeruginosa Sesquiterpenoids Single crystals Solanum lyratum X-ray diffraction |
title | Antibacterial sesquiterpenoids from Solanum lyratum |
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