Potential Role of Akkermansia muciniphila in Parkinson’s Disease and Other Neurological/Autoimmune Diseases

The composition of the gut microbiota, including Akkermansia muciniphila ( A. muciniphila ), is altered in many neurological diseases and may be involved in the pathophysiological processes of Parkinson’s disease (PD). A. muciniphila , a mucin-degrading bacterium, is a potential next-generation micr...

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Bibliographic Details
Published in:Current medical science 2021-12, Vol.41 (6), p.1172-1177
Main Authors: Fang, Xin, Li, Fang-jun, Hong, Dao-jun
Format: Article
Language:English
Subjects:
Akkermansia
Autoimmune Diseases - physiopathology
Gastrointestinal Microbiome
Humans
Medicine
Medicine & Public Health
Parkinson Disease - immunology
Parkinson Disease - physiopathology
Verrucomicrobia
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Summary:The composition of the gut microbiota, including Akkermansia muciniphila ( A. muciniphila ), is altered in many neurological diseases and may be involved in the pathophysiological processes of Parkinson’s disease (PD). A. muciniphila , a mucin-degrading bacterium, is a potential next-generation microbe that has anti-inflammatory properties and is responsible for keeping the body healthy. As the role of A. muciniphila in PD has become increasingly apparent, we discuss the potential link between A. muciniphila and various neurological diseases (including PD) in the current review.
ISSN:2096-5230
2523-899X
DOI:10.1007/s11596-021-2464-5