Outcomes among CMV‐mismatched and highly sensitized kidney transplants recipients who develop neutropenia

Limited data exist on the incidence and clinical outcomes of neutropenia among kidney transplant recipients. Our study included 572 adults who received a kidney transplant at the University of California, San Francisco Medical Center between 2012 and 2018, and were CMV‐mismatched or had a PRA ≥ 80%....

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Bibliographic Details
Published in:Clinical transplantation 2022-04, Vol.36 (4), p.e14583-n/a
Main Authors: Brar, Sandeep, Berry, Reyoot, Raval, Amit D., Tang, Yuexin, Vincenti, Flavio, Skartsis, Nikolaos
Format: Article
Language:English
Subjects:
Adult
complication
Cytomegalovirus Infections - complications
Cytomegalovirus Infections - etiology
drug toxicity
Female
Graft Rejection - drug therapy
Graft Rejection - etiology
Humans
Kidney Transplantation - adverse effects
Middle Aged
mycophenolate mofetil
Neutropenia - drug therapy
Neutropenia - etiology
Retrospective Studies
side effects
Transplant Recipients
Valganciclovir - therapeutic use
valgancylcovir
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Summary:Limited data exist on the incidence and clinical outcomes of neutropenia among kidney transplant recipients. Our study included 572 adults who received a kidney transplant at the University of California, San Francisco Medical Center between 2012 and 2018, and were CMV‐mismatched or had a PRA ≥ 80%. Recipients with HIV, Hepatitis B and C, and primary non‐function were excluded. Participants were followed for at least 1 year after transplantation. Neutropenia was defined as absolute neutrophil count 
ISSN:0902-0063
1399-0012
DOI:10.1111/ctr.14583