Serum uric acid levels associated with biochemical parameters linked to preeclampsia severity and to adverse perinatal outcomes

Aims Evaluating the association between serum uric acid levels and biochemical parameters linked to preeclampsia (PE) severity and to adverse perinatal outcomes. Methods Cross-sectional study. Information about gestational and biochemical parameters were collected before delivery, whereas perinatal...

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Published in:Archives of gynecology and obstetrics 2022-06, Vol.305 (6), p.1453-1463
Main Authors: de Mendonça, Elaine Luiza Santos Soares, da Silva, João Victor Farias, Mello, Carolina Santos, de Oliveira, Alane Cabral Menezes
Format: Article
Language:English
Subjects:
Cross-Sectional Studies
Endocrinology
Female
General Gynecology
Gynecology
Human Genetics
Humans
Hyperuricemia - complications
Infant, Newborn
Infant, Newborn, Diseases
Infant, Small for Gestational Age
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Pre-Eclampsia
Preeclampsia
Pregnancy
Uric Acid
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Summary:Aims Evaluating the association between serum uric acid levels and biochemical parameters linked to preeclampsia (PE) severity and to adverse perinatal outcomes. Methods Cross-sectional study. Information about gestational and biochemical parameters were collected before delivery, whereas perinatal outcomes were observed after it. Pregnant women were divided into hyperuricemia—HU (uric acid ≥ 6 mg/dL) or normouricemia (uric acid, 2.6–5.9 mg/dL) groups. Poisson regression models (prevalence ratio—PR; 95% confidence interval—95% CI), multinomial logistic regression (odds ratio—OR; 95% CI), and Pearson's correlation (correlation coefficient— r ) were applied by taking into consideration p  
ISSN:1432-0711
0932-0067
1432-0711
DOI:10.1007/s00404-021-06313-2