Associations between cortical activation and network interaction during sleep

• Published in: Behavioural brain research 2022-03, Vol.422, p.113751-113751, Article 113751
• Main Authors: Wang, Kejie, Zhang, Yangting, Zhu, Yongpeng, Luo, Yuxi
• Format: Article
• Language: English
• Subjects: Cortical activation; EEG; Network connectivity; Sleep
• ISSN: 0166-4328; 1872-7549
• DOI: 10.1016/j.bbr.2022.113751

Cortical activation and network interaction, two characterizations of the cortical states, are separately studied in most previous studies. To further clarify the underlying mechanism, the association between these two indicators during sleep was investigated in this study. Twenty healthy individuals were enrolled and all of them underwent overnight polysomnography (PSG) recording. The relative spectral powers and the phase transfer entropy (PTE) of various frequency components were extracted from 6 electroencephalographic (EEG) channels, to assess the cortical activation and network interaction, respectively. Pearson correlation coefficient was employed to estimate their associations. The results suggested that there was a negative correlation between spectral power and phase transfer entropy in δ and α frequency bands during sleep. As the sleep deepened, an increased negative correlation in the δ frequency band was noted, but the negative correlation became less extreme in the α frequency band. The extremum of the correlation coefficient was noted in δ of N3, and α of Wake. Overall, this study provides a connection between these two cortical activity assessments, especially reveals the variable characteristics of different frequency components, which is conducive to better understand sleep state. •Associations between cortical activation and network interaction was studied using rPSD and PTE.•The coupling of cortical activation and network interaction varied in different frequency band.•As sleep deepens, negative correlation increased in the δ, and vice versa for α frequency band.•The negative correlation peaked in the N3 of δ and Wake of α.