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Effects of Radiofrequency Catheter Ablation on Cardiac Reserve Using Preload Stress Echocardiography in Paroxysmal and Persistent Atrial Fibrillation

The effects of catheter ablation on exercise tolerance and quality of life in patients with atrial fibrillation (AF) have been reported. We assessed cardiac function in more detail using the leg positive pressure (LPP) technique and found that contractile reserve is particularly important in relatio...

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Published in:The American journal of cardiology 2022-04, Vol.168, p.71-77
Main Authors: Ishii, Nao, Kusunose, Kenya, Shono, Ayu, Matsumoto, Kensuke, Nishio, Susumu, Yamaguchi, Natsumi, Hirata, Yukina, Matsuura, Tomomi, Ise, Takayuki, Yamaguchi, Koji, Yagi, Shusuke, Fukuda, Daiju, Yamada, Hirotsugu, Soeki, Takeshi, Wakatsuki, Tetsuzo, Sata, Masataka
Format: Article
Language:English
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Summary:The effects of catheter ablation on exercise tolerance and quality of life in patients with atrial fibrillation (AF) have been reported. We assessed cardiac function in more detail using the leg positive pressure (LPP) technique and found that contractile reserve is particularly important in relation to exercise tolerance and prognosis. In this study, we used the LPP technique to examine changes in contractile reserve immediately after ablation and 6 months later. We prospectively enrolled patients who underwent catheter ablation for AF at 2 institutes. We performed LPP stress echocardiography 2 to 3 days after (FU-1) and 6 months after (FU-2) ablation to examine changes in cardiac function indexes. The primary end point was improvement in contractile reserve. Ultimately, 109 patients (mean age 67.4 ± 9.6 years; 70% men) underwent 2 sessions of LPP stress echocardiography. The median CHA2DS2-VASC score was 2 (interquartile range 13). From FU-1 to FU-2, the change in the stroke volume index after the LPP maneuver increased in patients with paroxysmal and persistent AF with low CHA2DS2-VASC scores (both p
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2021.12.026