The Effects of Multi-Domain Interventions on Cognition: A Systematic Review

This review aimed to evaluate the effects of multi-domain interventions on cognition among individuals without dementia. Multi-domain interventions refer to those combining any single preventive measure such as physical activity, cognitive training, and/or nutrition to prevent dementia. Seventeen st...

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Bibliographic Details
Published in:Western Journal of Nursing Research 2022-12, Vol.44 (12), p.1134-1154
Main Authors: Ahn, Sangwoo, Chung, Jae Woo, Crane, Monica K., Bassett, David R., Anderson, Joel G.
Format: Article
Language:English
Subjects:
Aged
Alzheimer's disease
Clinical significance
Cognition
Cognitive ability
Cognitive skills training
Dementia
Dementia - therapy
Episodic memory
Executive Function
Exercise
Health education
Humans
Intervention
Memory, Episodic
Nurses
Nutrition
Physical activity
Systematic review
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Summary:This review aimed to evaluate the effects of multi-domain interventions on cognition among individuals without dementia. Multi-domain interventions refer to those combining any single preventive measure such as physical activity, cognitive training, and/or nutrition to prevent dementia. Seventeen studies were included (n = 10,056 total participants; mean age = 73 years), eight of which were rated as strong in quality while the other nine showed moderate quality. The standardized mean difference (SMD; d) was used to calculate the effect size for each included study. Multi-domain interventions consisting of physical activity, cognitive training, cardioprotective nutrition, and/or cardiovascular health education exerted beneficial effects on global cognition, episodic memory, and/or executive function with very small to moderate effect sizes (0.16–0.77). Nurses may consider combining these components to potentially stave off dementia. Future research is warranted to identify the optimal multi-domain intervention components that can induce clinically significant beneficial effects on cognition.
ISSN:0193-9459
1552-8456
DOI:10.1177/01939459211032272