Biomarkers responses and polybrominated diphenyl ethers and their methoxylated analogs measured in Sparus aurata from the Lagoon of Bizerte, Tunisia

• Published in: Environmental science and pollution research international 2022-05, Vol.29 (25), p.38618-38632
• Main Authors: Ben Ameur, Walid, El Megdiche, Yassine, Ennaceur, Soukaina, Mhadhbi, Takoua, Ben Hassine, Sihem, Annabi, Ali, de Lapuente, Joaquin, Driss, Mohamed Ridha, Borràs, Miquel, Eljarrat, Ethel
• Format: Article
• Language: English
• Subjects: Aquatic Pollution; Atmospheric Protection/Air Quality Control/Air Pollution; Biomarkers; Biomonitoring; Bromination; Catalase; Deoxyribonucleic acid; DNA; DNA damage; Earth and Environmental Science; Ecotoxicology; Environment; Environmental Chemistry; Environmental Health; Environmental impact; Environmental science; Ethers; Fish; Lagoons; Malondialdehyde; Organobromine compounds; Pollutants; Pollution levels; Polybrominated diphenyl ethers; Research Article; Sparus aurata; Superoxide dismutase; Waste Water Technology; Water Management; Water Pollution Control
• ISSN: 0944-1344; 1614-7499
• DOI: 10.1007/s11356-022-18769-z

This study aimed to the examination of the levels and effects of organobromine compounds (polybrominated diphenyl ethers: PBDEs and methoxylated brominated diphenyl ethers: MeO-PBDEs), in Sparus aurata native to the Lagoon of Bizerte. For that, different biomarkers of exposure (somatic indices, superoxide dismutase, and catalase activities) and effect (malondialdehyde level, histopathologic alterations, and DNA damage) as well as pollutant levels were measured in specimens collected from this impacted ecosystem and the Mediterranean Sea as a reference site. Bizerte Lagoon PBDE fish levels were higher than the Mediterranean Sea, whereas MeO-PBDEs were higher in the reference site. Fish from Bizerte Lagoon presented a higher hepatosomatic index, lower catalase and superoxide dismutase activity, higher level of malondialdehyde, and higher percentage of DNA tail in comparison to fish from the reference area. The histological study of the liver indicated substantial lesions in fish from the polluted site. The results showed strong positive correlations between the concentrations of the PBDE or MeO-PBDE and the MDA and DNA tail % levels and negative correlations for the activities of enzymes of SOD and CAT. Consequently, these findings could suggest a potential link between exposure to these pollutants and the observed biomarker responses in the Bizerte Lagoon seabream. Taken together, these results highlight the importance of biomarker selection and the selected sentinel fish species as useful tools for biomonitoring of aquatic pollution.