Oral versus intravenous paracetamol for patent ductus arteriosus closure in preterm infants

Background To examine whether oral administration of paracetamol as a first-line agent had a greater effect on the closure of a patent ductus arteriosus than the intravenous route. Methods We performed a retrospective study of preterm infants (

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Bibliographic Details
Published in:Pediatric research 2022-10, Vol.92 (4), p.1146-1152
Main Authors: Gover, Ayala, Levy, Philip T., Rotschild, Avi, Golzman, Marcelo, Molad, Michal, Lavie-Nevo, Karen, Kessel, Irena
Format: Article
Language:English
Subjects:
Acetaminophen
Analgesics
Clinical Research Article
Congenital diseases
Coronary vessels
Ductus Arteriosus, Patent - drug therapy
Gestational age
Humans
Ibuprofen - therapeutic use
Infant, Newborn
Infant, Premature
Medicine
Medicine & Public Health
Newborn babies
Oral administration
Pediatric Surgery
Pediatrics
Premature babies
Prospective Studies
Retrospective Studies
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Description
Summary:Background To examine whether oral administration of paracetamol as a first-line agent had a greater effect on the closure of a patent ductus arteriosus than the intravenous route. Methods We performed a retrospective study of preterm infants (
ISSN:0031-3998
1530-0447
DOI:10.1038/s41390-022-01944-w