Difficulties in emotion regulation in bipolar disorder: A systematic review and meta-analysis

•A global impairment of emotional regulation is present bipolar disorders.•The extent of this impairment is lower relative to borderline personality disorder•Emotional dysregulation should a target of bipolar disorder treatment Bipolar disorder (BD) is a severe mental disorder characterized by mood...

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Published in:Journal of affective disorders 2022-04, Vol.302, p.352-360
Main Authors: Miola, Alessandro, Cattarinussi, Giulia, Antiga, Gilberto, Caiolo, Stefano, Solmi, Marco, Sambataro, Fabio
Format: Article
Language:English
Subjects:
Bipolar disorder
Bipolar Disorder - psychology
Borderline personality disorder
Borderline Personality Disorder - psychology
Cross-Sectional Studies
Difficulties in emotion regulation
Emotional Regulation
Emotions
Humans
Mania
Meta-analysis
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Summary:•A global impairment of emotional regulation is present bipolar disorders.•The extent of this impairment is lower relative to borderline personality disorder•Emotional dysregulation should a target of bipolar disorder treatment Bipolar disorder (BD) is a severe mental disorder characterized by mood swings and functional impairment. Although alterations in emotional regulation (ER) are a key feature, a comprehensive meta-analysis on abnormalities in emotion regulation in BD is still lacking. We performed a random-effects meta-analysis on studies comparing the ER measured with the Difficulties in Emotion Regulation Scale (DERS) in BD and healthy controls (HC) or borderline personality disorder (BPD) and calculated the standardized mean difference (SMD) of the total DERS score between those with BD and HC (primary outcome). Secondary outcomes were the SMD of the DERS subscales between BD and HC, as well as the SMD of the total score of DERS and the subscales between BD and BPD. Twelve studies (858 BD, 540 BPD, 285 HC) were included. Compared to HC, BD showed significantly higher total DERS score (k=8, SMD 0.962, p
ISSN:0165-0327
1573-2517
DOI:10.1016/j.jad.2022.01.102