SARS‐CoV‐2‐related and Covid‐19 vaccine‐induced thromboembolic events: A comparative review

Since the start of the pandemic, thrombotic events have been a well‐known and severe complication associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. Nevertheless, the initiation of vaccination programs brought another rare yet highly fatal thrombotic event, vacci...

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Published in:Reviews in Medical Virology 2022-07, Vol.32 (4), p.e2327-n/a
Main Authors: Afshar, Zeinab Mohseni, Barary, Mohammad, Babazadeh, Arefeh, Hosseinzadeh, Rezvan, Alijanpour, Amirmasoud, Miri, Seyed Rouhollah, Sio, Terence T., Sullman, Mark J. M., Carson‐Chahhoud, Kristin, Langer, Florian, Ebrahimpour, Soheil
Format: Article
Language:English
Subjects:
Coronaviruses
COVID-19 vaccines
Covid‐19
Risk factors
SARS‐CoV‐2
Severe acute respiratory syndrome coronavirus 2
Thrombocytopenia
Thromboembolism
thrombosis
Vaccines
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Summary:Since the start of the pandemic, thrombotic events have been a well‐known and severe complication associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. Nevertheless, the initiation of vaccination programs brought another rare yet highly fatal thrombotic event, vaccine‐induced immune thrombotic thrombocytopaenia, which has caused extensive debate regarding the safety of vaccines. This review defines the thromboembolic events following infection and vaccination, identifies their risk factors, describes their pathophysiology, and discusses their management, treatment, and prevention.
ISSN:1052-9276
1099-1654
DOI:10.1002/rmv.2327