Impact of thyroid dysfunction on short-term outcomes and long-term mortality in patients with pulmonary embolism

A large body of evidence suggest an impact of thyroid function on outcomes of cardiovascular diseases, but results for acute pulmonary embolism (PE) are sparse. We analysed the impact of hypothyroidism as well as hyperthyroidism on the short and long-term outcomes of patients with acute PE. The impa...

Full description

Saved in:
Bibliographic Details
Published in:Thrombosis research 2022-03, Vol.211, p.70-78
Main Authors: Pohl, Kristina R., Hobohm, Lukas, Krieg, Valentin J., Sentler, Carmen, Rogge, Nina I.J., Steimke, Laura, Ebner, Matthias, Lerchbaumer, Markus, Hasenfuß, Gerd, Konstantinides, Stavros, Lankeit, Mareike, Keller, Karsten
Format: Article
Language:English
Subjects:
Aged
Female
Hospital Mortality
Humans
Hyperthyroidism
Hyperthyroidism - complications
Hypothyroidism
Hypothyroidism - complications
Male
Pulmonary embolism
Pulmonary Embolism - complications
Thyroid
Thyroid Diseases - complications
TSH
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A large body of evidence suggest an impact of thyroid function on outcomes of cardiovascular diseases, but results for acute pulmonary embolism (PE) are sparse. We analysed the impact of hypothyroidism as well as hyperthyroidism on the short and long-term outcomes of patients with acute PE. The impact was compared to the group of euthyroid PE patients as reference group. Overall, 831 PE patients (median age 69 [IQR 56–77] years; 52.2% females) were analysed. Among these, 734 patients (88.3%) were classified as euthyroid, 40 (4.8%) as hypothyroid and 57 (6.9%) as hyperthyroid. PE patients with hypothyroidism had higher rates of adverse in-hospital outcomes (37.5% vs. 11.6%, P 
ISSN:0049-3848
1879-2472
DOI:10.1016/j.thromres.2022.01.014