Influence of Prostate Artery Embolization on Different Qualities of Lower Urinary Tract Symptoms Due to Benign Prostatic Obstruction

In our study, prostate artery embolization (PAE) alleviated significantly all typical urinary symptoms related to benign prostatic obstruction, with similar improvement of voiding and storage issues for at least 2 yr. PAE decreased the need for medication remarkably. Our data can help inform patient...

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Bibliographic Details
Published in:European urology focus 2022-09, Vol.8 (5), p.1323-1330
Main Authors: Theurich, Anne Tabea, Leistritz, Lutz, Leucht, Katharina, Franiel, Tobias, Teichgräber, Ulf, Foller, Susan, Grimm, Marc-Oliver
Format: Article
Language:English
Subjects:
Benign prostatic obstruction
International prostatic symptom score
Lower urinary tract symptoms
Prostate artery embolization
Storage symptoms
Voiding symptoms
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Summary:In our study, prostate artery embolization (PAE) alleviated significantly all typical urinary symptoms related to benign prostatic obstruction, with similar improvement of voiding and storage issues for at least 2 yr. PAE decreased the need for medication remarkably. Our data can help inform patients about the method. Prostate artery embolization (PAE) is an increasingly used minimally invasive treatment for lower urinary tract symptoms secondary to benign prostatic obstruction (BPO) To analyze the impact of PAE on voiding and storage symptoms. Between July 2014 and May 2019, 351 consecutive men with BPO who underwent PAE were included in a single-center study. PAE is an interventional radiological procedure embolizing the prostatic arteries with microspheres. The primary endpoint represented assessment of the International Prostatic Symptom Score (IPSS) at baseline and at 1, 3, 6, 12, and 24 mo after PAE. Secondary endpoints comprised assessment of IPSS quality of life (QoL), International Index of Erectile Function, peak urinary flow rate, postvoid residual volume, prostate volume, and prostate-specific antigen at the same time points. Data were analyzed using standard statistical methods, generalized estimating equations (symptom improvement over time as odds ratios), and McNemar-Bowker test (degree of improvement compared between symptoms). Clinical success rates for PAE were 68%, 73%, and 66% at 1, 12, and 24 mo, respectively. The median IPSS improved significantly from 22 to 10 points after 2 yr (p 
ISSN:2405-4569
2405-4569
DOI:10.1016/j.euf.2022.01.011