Stereotactic IntraCerebral Underwater Blood Aspiration (SCUBA) Improves Survival Following Intracerebral Hemorrhage as Compared with Predicted Mortality

• Published in: World neurosurgery 2022-05, Vol.161, p.e289-e294
• Main Authors: Shapiro, Steven D., Alkayyali, Miryam, Reynolds, Alexandra, Reilly, Kaitlin, Selim, Magdy, Dangayach, Neha, Mocco, J., Kellner, Christopher P., Liang, John W.
• Format: Article
• Language: English
• Subjects: Cerebral Hemorrhage - surgery; Hematoma; Humans; ICH score; Imaging, Three-Dimensional; Intracranial hemorrhage; Respiration Disorders; Stroke; United States
• ISSN: 1878-8750; 1878-8769
• DOI: 10.1016/j.wneu.2022.01.123

Recent publications on minimally invasive surgery (MIS) for hematoma evacuation have suggested survival benefits in select patients. Since 2015, our center has been performing an MIS technique using continuous irrigation with aspiration through an endoscope (stereotactic intracerebral underwater blood aspiration [SCUBA]). It is unknown how these patient outcomes compare with intracerebral hemorrhage (ICH) score predictions. Our aim is to determine if SCUBA patients had better 30-day mortality than predicted by their presenting ICH score. Retrospective review of consecutively admitted patients who underwent SCUBA between December 2015 and March 2019. Operative criteria for MIS evacuation included supratentorial hematoma volume ≥15 mL, age >18, National Institutes of Health Stroke Scale score ≥6, and modified Rankin Scale (mRS) score ≤3. Demographic, radiographic, and clinical data were collected prospectively. The prespecified primary outcome was observed 30-day mortality of SCUBA patients compared with predicted mortality by ICH score on presentation. One-hundred and fifteen patients underwent SCUBA for hematoma evacuation. Initial mean ICH volume was 51.4 mL (standard deviation 33.9 mL), with a median National Institutes of Health Stroke Scale score of 17 and ICH score of 2. At 1 month, 12 of the 115 SCUBA patients had passed away (30-day mortality rate 10.4%). This was significantly lower than the predicted mortality of 35.1% when calculated using the presenting ICH score (χ2 (1, N = 115) = 9.5, P < 0.0001), equating to an absolute risk reduction of 24.7%. This study suggests that minimally invasive hematoma evacuation with the SCUBA technique for ICH may reduce predicted 30-day mortality, with a number needed to treat of 4 to prevent 1 mortality.