The role of platelet-rich plasma in microlaryngeal surgery: a randomised, controlled trial

Platelet-rich plasma has gained interest over the two last decades, mainly because of its role in regenerative medicine. This work aimed to assess the role of intra-operative local application of platelet-rich plasma gel in the improvement of quality of voice after microlaryngeal surgery. This was a...

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Bibliographic Details
Published in:Journal of laryngology and otology 2022-08, Vol.136 (8), p.737-741
Main Authors: Gaafar, A, Eldeghiedy, A, ElMaghraby, R, Nouh, I, Donia, M
Format: Article
Language:English
Subjects:
Blood platelets
Cysts
Edema
Growth factors
Main Article
Otolaryngology
Plasma
Platelets
Polyps
Regenerative medicine
Software
Standard deviation
Surgery
Symmetry
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Summary:Platelet-rich plasma has gained interest over the two last decades, mainly because of its role in regenerative medicine. This work aimed to assess the role of intra-operative local application of platelet-rich plasma gel in the improvement of quality of voice after microlaryngeal surgery. This was a prospective comparative study that included 40 patients undergoing microlaryngeal surgery for benign vocal fold lesions. There were two groups divided equally into study group A and control group B. The assessment of voice was performed by videostroboscopy and acoustic analysis pre-operatively and at two weeks and one and three months post-operatively. The data demonstrated that all the stroboscopic and acoustic parameters showed significant improvement in both groups. Group A showed significant improvement regarding acoustic parameters at the third post-operative follow up when compared with group B. Platelet-rich plasma has a beneficial effect on voice quality following microlaryngeal surgery based in particular on acoustic parameters.
ISSN:0022-2151
1748-5460
DOI:10.1017/S0022215121004564