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Short-term effects and economic burden assessment of ambient air pollution on hospitalizations for schizophrenia

The evidence on the health and economic impacts of air pollution with schizophrenia is scarce, especially in developing countries. In this study, we aimed to systemically examine the short-term effects of PM 2.5 (particulate matter ≤ 2.5 μm in diameter), PM 10 (≤ 10 μm in diameter), NO 2 (nitrogen d...

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Published in:Environmental science and pollution research international 2022-06, Vol.29 (30), p.45449-45460
Main Authors: Ji, Yanhu, Liu, Bin, Song, Jian, Pan, Rubing, Cheng, Jian, Wang, Heng, Su, Hong
Format: Article
Language:English
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Summary:The evidence on the health and economic impacts of air pollution with schizophrenia is scarce, especially in developing countries. In this study, we aimed to systemically examine the short-term effects of PM 2.5 (particulate matter ≤ 2.5 μm in diameter), PM 10 (≤ 10 μm in diameter), NO 2 (nitrogen dioxide), SO 2 (sulfur dioxide), CO (carbon monoxide), and O 3 (ozone) on hospital admissions for schizophrenia in a Chinese coastal city (Qingdao) and to further assess the corresponding attributable risk and economic burden. A generalized additive model (GAM) was applied to model the impact of air pollution on schizophrenia, and the corresponding economic burden including the direct costs (medical expenses) and indirect costs (productivity loss). Stratified analyses were also performed by age, gender, and season (warm or cold). Our results showed that for a 10 μg/m 3 increase in the concentrations of PM 2.5 , PM 10 , SO 2 , and CO at lag5, the corresponding relative risks (RRs) were 1.0160 (95% CI: 1.0038–1.0282), 1.0097 (1.0018–1.0177), 1.0738 (1.0222–1.01280), and 1.0013 (1.0001–1.0026), respectively. However, no significant effect of NO 2 or O 3 on schizophrenia admissions was found. The stratified analysis indicated that females and younger individuals (
ISSN:0944-1344
1614-7499
DOI:10.1007/s11356-022-19026-z