Hepatitis C virus micro‐elimination within a clinic for people with HIV: challenges in the home stretch

Objectives To describe a pharmacist‐led campaign aimed at reducing the proportion of people with HIV with ongoing chronic hepatitis C virus (HCV) infection and delineating barriers to HCV care in this patient population. Methods An electronic report and retrospective chart review were used to identi...

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Bibliographic Details
Published in:HIV medicine 2022-08, Vol.23 (7), p.801-806
Main Authors: Hanna, Jaklin, Sufian, Jihan, Suh, Jin S., Jimenez, Humberto R.
Format: Article
Language:English
Subjects:
Bivariate analysis
care cascade
Chronic infection
clinical pharmacists
direct‐acting antivirals
Drug use
Hepatitis
Hepatitis C
HIV
HIV/HCV coinfection
Human immunodeficiency virus
Mental health
Patients
Pharmacists
Recreational use
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Summary:Objectives To describe a pharmacist‐led campaign aimed at reducing the proportion of people with HIV with ongoing chronic hepatitis C virus (HCV) infection and delineating barriers to HCV care in this patient population. Methods An electronic report and retrospective chart review were used to identify patients who remained with HCV infections after a previous treatment initiative. A clinical pharmacist and pharmacy resident approached the remaining HCV patients during their routine visits for HIV care to offer and coordinate direct‐acting antiviral (DAA) treatment. The primary end‐point was to compare the prevalence of chronic HCV before and after the intervention period. Barriers to care were also evaluated, with logistic regression performed to identify predictors of sustained virologic response (SVR) attainment. Results Forty‐six patients were included in the analysis (4.2% of clinic population), with HCV prevalence falling to 0.6% (six patients) by the end of the study (p 
ISSN:1464-2662
1468-1293
DOI:10.1111/hiv.13241