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Seasonal variation in high-risk phenotypes of cutaneous malignant melanoma diagnosed in Eastern England: An observational study

Despite seasonal variation in malignant melanoma diagnosis being well described, data on the annual variation in high-risk melanomas are scarce. We set out to investigate the relationship between seasonality, the incidence of melanoma, and the distribution of melanoma characteristics, including Bres...

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Bibliographic Details
Published in:Journal of plastic, reconstructive & aesthetic surgery reconstructive & aesthetic surgery, 2022-06, Vol.75 (6), p.1923-1930
Main Authors: Sharp, O., Garioch, J., Moncrieff, M.
Format: Article
Language:English
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Summary:Despite seasonal variation in malignant melanoma diagnosis being well described, data on the annual variation in high-risk melanomas are scarce. We set out to investigate the relationship between seasonality, the incidence of melanoma, and the distribution of melanoma characteristics, including Breslow thickness, ulceration, mitotic rate, lymphovascular and perineural invasion, and the presence of microsatellites. Primary cutaneous malignant melanomas diagnosed between 2011 and 2019 in Eastern England were identified from our prospectively maintained melanoma database (n = 2199). These were analysed by year and season of diagnosis, patient demographics, and melanoma characteristics. There was a variation in rates of melanoma diagnosis across the year, with Summer having the highest incidence (p 
ISSN:1748-6815
1878-0539
DOI:10.1016/j.bjps.2022.01.002