Recent advances in construction and regulation of yeast cell factories

The past decade has witnessed the rapid progress in development of synthetic biology, and advances in construction of yeast cell factories open vast opportunities for green and sustainable production of chemicals. Focusing on the progress in yeast engineering for production of plant natural products...

Full description

Saved in:
Bibliographic Details
Published in:World journal of microbiology & biotechnology 2022-04, Vol.38 (4), p.57-57, Article 57
Main Authors: Jiao, Xue, Gu, Yuehao, Zhou, Pingping, Yu, Hongwei, Ye, Lidan
Format: Article
Language:English
Subjects:
Applied Microbiology
Biochemistry
Biomedical and Life Sciences
Biotechnology
Environmental Engineering/Biotechnology
Factories
Gene Editing
Genome editing
Genomes
Industrial engineering
Life Sciences
Localization
Manufacturing engineering
Metabolic Engineering
Microbiology
Natural products
Review
Saccharomyces cerevisiae - genetics
Saccharomyces cerevisiae - metabolism
Sustainable production
Synthetic Biology
Yarrowia - genetics
Yarrowia - metabolism
Yeast
Yeasts
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c375t-d5e24e7e432089b9394fc6f03f1ddf767ce0337ff7d29cd93abcfad9a52c63bc3
cites cdi_FETCH-LOGICAL-c375t-d5e24e7e432089b9394fc6f03f1ddf767ce0337ff7d29cd93abcfad9a52c63bc3
container_end_page 57
container_issue 4
container_start_page 57
container_title World journal of microbiology & biotechnology
container_volume 38
creator Jiao, Xue
Gu, Yuehao
Zhou, Pingping
Yu, Hongwei
Ye, Lidan
description The past decade has witnessed the rapid progress in development of synthetic biology, and advances in construction of yeast cell factories open vast opportunities for green and sustainable production of chemicals. Focusing on the progress in yeast engineering for production of plant natural products in the last 5 years, this review introduces different yeast chassis used for cell factory construction, including Saccharomyces cerevisiae , Yarrowia lipolytica and Komagataella phaffii , together with the emerging genome editing tools. The metabolic regulation strategies developed for yeast engineering are highlighted, such as subcellular pathway localization dynamic regulation, and transporter engineering. C1-based chemical bioproduction by engineered yeast is also covered. Finally, the existing challenges and future prospects in creating efficient yeast cell factories are summarized.
doi_str_mv 10.1007/s11274-022-03241-4
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2629887064</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2629162357</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-d5e24e7e432089b9394fc6f03f1ddf767ce0337ff7d29cd93abcfad9a52c63bc3</originalsourceid><addsrcrecordid>eNp9kMFKAzEQhoMotlZfwIMsePGymmSym-YoxapQEETPIU0mZUubrcmu0Ld3260KHjwNw3zzz_ARcsnoLaNU3iXGuBQ55TynwAXLxREZskJCTpXkx2RIVaFyUAoG5CylJaXdmoJTMoCCSSG4GJLpK1oMTWbcpwkWU1aFzNYhNbG1TVWHzASXRVy0K7Nva59t0aQms7haZd7Ypo4VpnNy4s0q4cWhjsj79OFt8pTPXh6fJ_ez3IIsmtwVyAVKFMDpWM0VKOFt6Sl45pyXpbRIAaT30nFlnQIzt944ZQpuS5hbGJGbPncT648WU6PXVdq9YgLWbdK85Go8lrQUHXr9B13WbQzdd3uKlRw6VSPCe8rGOqWIXm9itTZxqxnVO8u6t6w7y3pvWe-irw7R7XyN7mflW2sHQA-kbhQWGH9v_xP7Bemzh6Y</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2629162357</pqid></control><display><type>article</type><title>Recent advances in construction and regulation of yeast cell factories</title><source>ABI/INFORM Global</source><source>Springer Link</source><creator>Jiao, Xue ; Gu, Yuehao ; Zhou, Pingping ; Yu, Hongwei ; Ye, Lidan</creator><creatorcontrib>Jiao, Xue ; Gu, Yuehao ; Zhou, Pingping ; Yu, Hongwei ; Ye, Lidan</creatorcontrib><description>The past decade has witnessed the rapid progress in development of synthetic biology, and advances in construction of yeast cell factories open vast opportunities for green and sustainable production of chemicals. Focusing on the progress in yeast engineering for production of plant natural products in the last 5 years, this review introduces different yeast chassis used for cell factory construction, including Saccharomyces cerevisiae , Yarrowia lipolytica and Komagataella phaffii , together with the emerging genome editing tools. The metabolic regulation strategies developed for yeast engineering are highlighted, such as subcellular pathway localization dynamic regulation, and transporter engineering. C1-based chemical bioproduction by engineered yeast is also covered. Finally, the existing challenges and future prospects in creating efficient yeast cell factories are summarized.</description><identifier>ISSN: 0959-3993</identifier><identifier>EISSN: 1573-0972</identifier><identifier>DOI: 10.1007/s11274-022-03241-4</identifier><identifier>PMID: 35174424</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Applied Microbiology ; Biochemistry ; Biomedical and Life Sciences ; Biotechnology ; Environmental Engineering/Biotechnology ; Factories ; Gene Editing ; Genome editing ; Genomes ; Industrial engineering ; Life Sciences ; Localization ; Manufacturing engineering ; Metabolic Engineering ; Microbiology ; Natural products ; Review ; Saccharomyces cerevisiae - genetics ; Saccharomyces cerevisiae - metabolism ; Sustainable production ; Synthetic Biology ; Yarrowia - genetics ; Yarrowia - metabolism ; Yeast ; Yeasts</subject><ispartof>World journal of microbiology &amp; biotechnology, 2022-04, Vol.38 (4), p.57-57, Article 57</ispartof><rights>The Author(s), under exclusive licence to Springer Nature B.V. 2022</rights><rights>2022. The Author(s), under exclusive licence to Springer Nature B.V.</rights><rights>The Author(s), under exclusive licence to Springer Nature B.V. 2022.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-d5e24e7e432089b9394fc6f03f1ddf767ce0337ff7d29cd93abcfad9a52c63bc3</citedby><cites>FETCH-LOGICAL-c375t-d5e24e7e432089b9394fc6f03f1ddf767ce0337ff7d29cd93abcfad9a52c63bc3</cites><orcidid>0000-0002-6248-8457 ; 0000-0002-9144-4496</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2629162357/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2629162357?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,11688,27924,27925,36060,36061,44363,74895</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35174424$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jiao, Xue</creatorcontrib><creatorcontrib>Gu, Yuehao</creatorcontrib><creatorcontrib>Zhou, Pingping</creatorcontrib><creatorcontrib>Yu, Hongwei</creatorcontrib><creatorcontrib>Ye, Lidan</creatorcontrib><title>Recent advances in construction and regulation of yeast cell factories</title><title>World journal of microbiology &amp; biotechnology</title><addtitle>World J Microbiol Biotechnol</addtitle><addtitle>World J Microbiol Biotechnol</addtitle><description>The past decade has witnessed the rapid progress in development of synthetic biology, and advances in construction of yeast cell factories open vast opportunities for green and sustainable production of chemicals. Focusing on the progress in yeast engineering for production of plant natural products in the last 5 years, this review introduces different yeast chassis used for cell factory construction, including Saccharomyces cerevisiae , Yarrowia lipolytica and Komagataella phaffii , together with the emerging genome editing tools. The metabolic regulation strategies developed for yeast engineering are highlighted, such as subcellular pathway localization dynamic regulation, and transporter engineering. C1-based chemical bioproduction by engineered yeast is also covered. Finally, the existing challenges and future prospects in creating efficient yeast cell factories are summarized.</description><subject>Applied Microbiology</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Environmental Engineering/Biotechnology</subject><subject>Factories</subject><subject>Gene Editing</subject><subject>Genome editing</subject><subject>Genomes</subject><subject>Industrial engineering</subject><subject>Life Sciences</subject><subject>Localization</subject><subject>Manufacturing engineering</subject><subject>Metabolic Engineering</subject><subject>Microbiology</subject><subject>Natural products</subject><subject>Review</subject><subject>Saccharomyces cerevisiae - genetics</subject><subject>Saccharomyces cerevisiae - metabolism</subject><subject>Sustainable production</subject><subject>Synthetic Biology</subject><subject>Yarrowia - genetics</subject><subject>Yarrowia - metabolism</subject><subject>Yeast</subject><subject>Yeasts</subject><issn>0959-3993</issn><issn>1573-0972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>M0C</sourceid><recordid>eNp9kMFKAzEQhoMotlZfwIMsePGymmSym-YoxapQEETPIU0mZUubrcmu0Ld3260KHjwNw3zzz_ARcsnoLaNU3iXGuBQ55TynwAXLxREZskJCTpXkx2RIVaFyUAoG5CylJaXdmoJTMoCCSSG4GJLpK1oMTWbcpwkWU1aFzNYhNbG1TVWHzASXRVy0K7Nva59t0aQms7haZd7Ypo4VpnNy4s0q4cWhjsj79OFt8pTPXh6fJ_ez3IIsmtwVyAVKFMDpWM0VKOFt6Sl45pyXpbRIAaT30nFlnQIzt944ZQpuS5hbGJGbPncT648WU6PXVdq9YgLWbdK85Go8lrQUHXr9B13WbQzdd3uKlRw6VSPCe8rGOqWIXm9itTZxqxnVO8u6t6w7y3pvWe-irw7R7XyN7mflW2sHQA-kbhQWGH9v_xP7Bemzh6Y</recordid><startdate>20220401</startdate><enddate>20220401</enddate><creator>Jiao, Xue</creator><creator>Gu, Yuehao</creator><creator>Zhou, Pingping</creator><creator>Yu, Hongwei</creator><creator>Ye, Lidan</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7TB</scope><scope>7TK</scope><scope>7U5</scope><scope>7U9</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K60</scope><scope>K6~</scope><scope>K9.</scope><scope>L.-</scope><scope>L7M</scope><scope>LK8</scope><scope>M0C</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-6248-8457</orcidid><orcidid>https://orcid.org/0000-0002-9144-4496</orcidid></search><sort><creationdate>20220401</creationdate><title>Recent advances in construction and regulation of yeast cell factories</title><author>Jiao, Xue ; Gu, Yuehao ; Zhou, Pingping ; Yu, Hongwei ; Ye, Lidan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-d5e24e7e432089b9394fc6f03f1ddf767ce0337ff7d29cd93abcfad9a52c63bc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Applied Microbiology</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Biotechnology</topic><topic>Environmental Engineering/Biotechnology</topic><topic>Factories</topic><topic>Gene Editing</topic><topic>Genome editing</topic><topic>Genomes</topic><topic>Industrial engineering</topic><topic>Life Sciences</topic><topic>Localization</topic><topic>Manufacturing engineering</topic><topic>Metabolic Engineering</topic><topic>Microbiology</topic><topic>Natural products</topic><topic>Review</topic><topic>Saccharomyces cerevisiae - genetics</topic><topic>Saccharomyces cerevisiae - metabolism</topic><topic>Sustainable production</topic><topic>Synthetic Biology</topic><topic>Yarrowia - genetics</topic><topic>Yarrowia - metabolism</topic><topic>Yeast</topic><topic>Yeasts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jiao, Xue</creatorcontrib><creatorcontrib>Gu, Yuehao</creatorcontrib><creatorcontrib>Zhou, Pingping</creatorcontrib><creatorcontrib>Yu, Hongwei</creatorcontrib><creatorcontrib>Ye, Lidan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Mechanical &amp; Transportation Engineering Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health &amp; Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>ProQuest Business Premium Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>ProQuest Biological Science Collection</collection><collection>ABI/INFORM Global</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest Science Journals</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest Biological Science Journals</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>World journal of microbiology &amp; biotechnology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jiao, Xue</au><au>Gu, Yuehao</au><au>Zhou, Pingping</au><au>Yu, Hongwei</au><au>Ye, Lidan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recent advances in construction and regulation of yeast cell factories</atitle><jtitle>World journal of microbiology &amp; biotechnology</jtitle><stitle>World J Microbiol Biotechnol</stitle><addtitle>World J Microbiol Biotechnol</addtitle><date>2022-04-01</date><risdate>2022</risdate><volume>38</volume><issue>4</issue><spage>57</spage><epage>57</epage><pages>57-57</pages><artnum>57</artnum><issn>0959-3993</issn><eissn>1573-0972</eissn><abstract>The past decade has witnessed the rapid progress in development of synthetic biology, and advances in construction of yeast cell factories open vast opportunities for green and sustainable production of chemicals. Focusing on the progress in yeast engineering for production of plant natural products in the last 5 years, this review introduces different yeast chassis used for cell factory construction, including Saccharomyces cerevisiae , Yarrowia lipolytica and Komagataella phaffii , together with the emerging genome editing tools. The metabolic regulation strategies developed for yeast engineering are highlighted, such as subcellular pathway localization dynamic regulation, and transporter engineering. C1-based chemical bioproduction by engineered yeast is also covered. Finally, the existing challenges and future prospects in creating efficient yeast cell factories are summarized.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>35174424</pmid><doi>10.1007/s11274-022-03241-4</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-6248-8457</orcidid><orcidid>https://orcid.org/0000-0002-9144-4496</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0959-3993
ispartof World journal of microbiology & biotechnology, 2022-04, Vol.38 (4), p.57-57, Article 57
issn 0959-3993
1573-0972
language eng
recordid cdi_proquest_miscellaneous_2629887064
source ABI/INFORM Global; Springer Link
subjects Applied Microbiology
Biochemistry
Biomedical and Life Sciences
Biotechnology
Environmental Engineering/Biotechnology
Factories
Gene Editing
Genome editing
Genomes
Industrial engineering
Life Sciences
Localization
Manufacturing engineering
Metabolic Engineering
Microbiology
Natural products
Review
Saccharomyces cerevisiae - genetics
Saccharomyces cerevisiae - metabolism
Sustainable production
Synthetic Biology
Yarrowia - genetics
Yarrowia - metabolism
Yeast
Yeasts
title Recent advances in construction and regulation of yeast cell factories
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T02%3A52%3A16IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Recent%20advances%20in%20construction%20and%20regulation%20of%20yeast%20cell%20factories&rft.jtitle=World%20journal%20of%20microbiology%20&%20biotechnology&rft.au=Jiao,%20Xue&rft.date=2022-04-01&rft.volume=38&rft.issue=4&rft.spage=57&rft.epage=57&rft.pages=57-57&rft.artnum=57&rft.issn=0959-3993&rft.eissn=1573-0972&rft_id=info:doi/10.1007/s11274-022-03241-4&rft_dat=%3Cproquest_cross%3E2629162357%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c375t-d5e24e7e432089b9394fc6f03f1ddf767ce0337ff7d29cd93abcfad9a52c63bc3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2629162357&rft_id=info:pmid/35174424&rfr_iscdi=true