Oxytocin detection at ppt level in human saliva by an extended-gate-type organic field-effect transistor

Herein, we report an extended-gate-type organic field-effect transistor (OFET) sensor for oxytocin. The fabricated OFET-based immunosensor has successfully detected oxytocin at a ppt level in human saliva with high recovery rates (96-102%). We believe our sensor would pave the way for the realizatio...

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Bibliographic Details
Published in:Analyst (London) 2022-03, Vol.147 (6), p.1055-1059
Main Authors: Ohshiro, Kohei, Sasaki, Yui, Zhou, Qi, Lyu, Xiaojun, Yamanashi, Yusuke, Nakahara, Katsumasa, Nagaoka, Hirokazu, Minami, Tsuyoshi
Format: Article
Language:English
Subjects:
Biosensing Techniques
Electrodes
Field effect transistors
Humans
Immunoassay
Immunosensors
Oxytocin
Saliva
Semiconductor devices
Transistors
Transistors, Electronic
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Summary:Herein, we report an extended-gate-type organic field-effect transistor (OFET) sensor for oxytocin. The fabricated OFET-based immunosensor has successfully detected oxytocin at a ppt level in human saliva with high recovery rates (96-102%). We believe our sensor would pave the way for the realization of portable sensors for healthcare monitoring.
ISSN:0003-2654
1364-5528
DOI:10.1039/d1an02188e