Inhibitory Effect of Acer truncatum Bunge Seed Coat Extract on Fatty Acid Synthase, Differentiation and Lipid Accumulation in 3T3-L1 Adipocytes

Acer truncatum Bunge is now widely cultivated throughout the world. Fatty acid synthase (FAS) is a potential target in the treatment of both obesity and cancer. Only a few FAS inhibitors have been reported. In this study, the inhibitory effect of A. truncatum seed coat (ESA) on FAS and the inhibitio...

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Bibliographic Details
Published in:	Molecules (Basel, Switzerland) Switzerland), 2022-02, Vol.27 (4), p.1324
Main Authors:	Liang, Yan, Kong, Fan, Ma, Xiaofeng, Shu, Qingyan
Format:	Article
Language:	English
Subjects:	Acer - chemistry Acer truncatum Bunge Adipocytes Adipocytes - drug effects Animals Body fat Cell Differentiation - drug effects Chromatography, High Pressure Liquid Diabetes Enzyme Activation - drug effects Enzyme Inhibitors - chemistry Enzyme Inhibitors - pharmacology Enzymes fatty acid synthase Fatty Acid Synthases - metabolism Fatty acids Gene expression inhibitor Investigations Lipid Metabolism - drug effects Lipids Mice Molecular Structure Obesity Plant Extracts - chemistry Plant Extracts - pharmacology Seeds Seeds - chemistry Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Tandem Mass Spectrometry
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