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Exercise capacity remains supernormal, though mildly reduced in middle-aged military personnel with Moderate to Severe Obstructive Sleep Apnea
Introduction The relationship between moderate to severe OSA and exercise capacity remains unclear. Prior studies showing a reduction in VO 2 max in this population have mostly involved middle-aged, overweight patients. We aimed to study this relationship in a similarly aged population of military p...
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| Published in: | Sleep & breathing 2023-03, Vol.27 (1), p.137-144 |
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| creator | Arora, Subodh K. Powell, Tyler A. Foster, Shannon N. Hansen, Shana L. Morris, Michael J. |
| description | Introduction
The relationship between moderate to severe OSA and exercise capacity remains unclear. Prior studies showing a reduction in VO
2
max in this population have mostly involved middle-aged, overweight patients. We aimed to study this relationship in a similarly aged population of military personnel with previously undiagnosed moderate to severe OSA.
Methods
We studied late-career male military personnel who underwent CPET and polysomnography (PSG). Patients were categorized either into an OSA group (apnea–hypopnea index (AHI) ≥ 15 events/h) or a control group (AHI |
| doi_str_mv | 10.1007/s11325-022-02587-1 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2633902628</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2633902628</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-6ce381cd3b73c5f4dc1077780c5bbf69ba1e47582f6e9b261b1c7014ada551423</originalsourceid><addsrcrecordid>eNp9kUtvFiEUhonR2Fr9Ay4MiRsXjnJggJll0_SW1HRRXRMGznwfzdwEprV_or-5tF_VxIULAofzvC-Xl5D3wL4AY_prAhBcVozzMmSjK3hB9kGWEjRrXz6tWdVK4HvkTUrXjEHdtPCa7AnJQbeC75P7418YXUhInV2sC_mORhxtmBJN64JxmuNoh880b-d1s6VjGPzwiPjVoadhKjveD1jZTSlLN2Qb72gRpnmacKC3IW_pt9ljtBlpnukV3mBEetmlHFeXww3SqwFxoYfLhPYtedXbIeG75_mA_Dg5_n50Vl1cnp4fHV5UTmiZK-VQNOC86LRwsq-9A6a1bpiTXdertrOAtZYN7xW2HVfQgdPl9dZbKaHm4oB82vkucf65YspmDMnhMNgJ5zUZroRoGVe8KejHf9DreY1TuZ3hjQIlFNSsUHxHuTinFLE3Swxj-QsDzDymZXZpmZKWeUrLQBF9eLZeuxH9H8nveAogdkAqrWmD8e_Z_7F9ALeCoac</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2861636140</pqid></control><display><type>article</type><title>Exercise capacity remains supernormal, though mildly reduced in middle-aged military personnel with Moderate to Severe Obstructive Sleep Apnea</title><source>Social Science Premium Collection</source><source>Springer Link</source><creator>Arora, Subodh K. ; Powell, Tyler A. ; Foster, Shannon N. ; Hansen, Shana L. ; Morris, Michael J.</creator><creatorcontrib>Arora, Subodh K. ; Powell, Tyler A. ; Foster, Shannon N. ; Hansen, Shana L. ; Morris, Michael J.</creatorcontrib><description>Introduction
The relationship between moderate to severe OSA and exercise capacity remains unclear. Prior studies showing a reduction in VO
2
max in this population have mostly involved middle-aged, overweight patients. We aimed to study this relationship in a similarly aged population of military personnel with previously undiagnosed moderate to severe OSA.
Methods
We studied late-career male military personnel who underwent CPET and polysomnography (PSG). Patients were categorized either into an OSA group (apnea–hypopnea index (AHI) ≥ 15 events/h) or a control group (AHI < 15 events/h). VO
2
max was compared between groups.
Results
170 male military personnel met criteria for the study. Mean AHI was 29.0/h in the OSA group (
n
= 58) versus 7.4/h in the controls (
n
= 112) while SpO
2
nadir was slightly lower (86.0% vs. 89.0%). Patients were of similar age (53.1 vs. 53.7 years), and BMI was slightly higher in the OSA group (27.5 kg/m
2
vs. 26.3 kg/m
2
). Percent-predicted VO
2
max was supernormal in both groups, though it was comparatively lower in the OSA group (117% vs. 125%;
p
< 0.001).
Conclusions
Military personnel with moderate to severe OSA were able to achieve supernormal VO
2
max values, yet had an 8% decrement in exercise capacity compared to controls. These findings suggest that OSA without significant hypoxemia may not significantly influence exercise capacity. It remains likely that the effects of untreated OSA on exercise capacity are complex and are affected by several variables including BMI, degree of associated hypoxemia, and regularity of exercise. Statistically lower VO
2
max noted in this study may suggest that untreated OSA in less fit populations may lead to significant decrements in exercise capacity.</description><identifier>ISSN: 1520-9512</identifier><identifier>EISSN: 1522-1709</identifier><identifier>DOI: 10.1007/s11325-022-02587-1</identifier><identifier>PMID: 35217932</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Aged ; Apnea ; Body weight ; Dentistry ; Exercise ; Exercise Tolerance ; Humans ; Hypoxemia ; Internal Medicine ; Male ; Maximum oxygen consumption ; Medicine ; Medicine & Public Health ; Middle age ; Middle Aged ; Military Personnel ; Neurology ; Otorhinolaryngology ; Overweight ; Pediatrics ; Pneumology/Respiratory System ; Sleep apnea ; Sleep Apnea, Obstructive - diagnosis ; Sleep Breathing Physiology and Disorders • Original Article ; Sleep disorders</subject><ispartof>Sleep & breathing, 2023-03, Vol.27 (1), p.137-144</ispartof><rights>This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2022</rights><rights>2022. This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply.</rights><rights>This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2022.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-6ce381cd3b73c5f4dc1077780c5bbf69ba1e47582f6e9b261b1c7014ada551423</citedby><cites>FETCH-LOGICAL-c375t-6ce381cd3b73c5f4dc1077780c5bbf69ba1e47582f6e9b261b1c7014ada551423</cites><orcidid>0000-0003-2850-8044</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2861636140/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2861636140?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,21394,27924,27925,33611,33612,43733,74221</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35217932$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Arora, Subodh K.</creatorcontrib><creatorcontrib>Powell, Tyler A.</creatorcontrib><creatorcontrib>Foster, Shannon N.</creatorcontrib><creatorcontrib>Hansen, Shana L.</creatorcontrib><creatorcontrib>Morris, Michael J.</creatorcontrib><title>Exercise capacity remains supernormal, though mildly reduced in middle-aged military personnel with Moderate to Severe Obstructive Sleep Apnea</title><title>Sleep & breathing</title><addtitle>Sleep Breath</addtitle><addtitle>Sleep Breath</addtitle><description>Introduction
The relationship between moderate to severe OSA and exercise capacity remains unclear. Prior studies showing a reduction in VO
2
max in this population have mostly involved middle-aged, overweight patients. We aimed to study this relationship in a similarly aged population of military personnel with previously undiagnosed moderate to severe OSA.
Methods
We studied late-career male military personnel who underwent CPET and polysomnography (PSG). Patients were categorized either into an OSA group (apnea–hypopnea index (AHI) ≥ 15 events/h) or a control group (AHI < 15 events/h). VO
2
max was compared between groups.
Results
170 male military personnel met criteria for the study. Mean AHI was 29.0/h in the OSA group (
n
= 58) versus 7.4/h in the controls (
n
= 112) while SpO
2
nadir was slightly lower (86.0% vs. 89.0%). Patients were of similar age (53.1 vs. 53.7 years), and BMI was slightly higher in the OSA group (27.5 kg/m
2
vs. 26.3 kg/m
2
). Percent-predicted VO
2
max was supernormal in both groups, though it was comparatively lower in the OSA group (117% vs. 125%;
p
< 0.001).
Conclusions
Military personnel with moderate to severe OSA were able to achieve supernormal VO
2
max values, yet had an 8% decrement in exercise capacity compared to controls. These findings suggest that OSA without significant hypoxemia may not significantly influence exercise capacity. It remains likely that the effects of untreated OSA on exercise capacity are complex and are affected by several variables including BMI, degree of associated hypoxemia, and regularity of exercise. Statistically lower VO
2
max noted in this study may suggest that untreated OSA in less fit populations may lead to significant decrements in exercise capacity.</description><subject>Aged</subject><subject>Apnea</subject><subject>Body weight</subject><subject>Dentistry</subject><subject>Exercise</subject><subject>Exercise Tolerance</subject><subject>Humans</subject><subject>Hypoxemia</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Maximum oxygen consumption</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle age</subject><subject>Middle Aged</subject><subject>Military Personnel</subject><subject>Neurology</subject><subject>Otorhinolaryngology</subject><subject>Overweight</subject><subject>Pediatrics</subject><subject>Pneumology/Respiratory System</subject><subject>Sleep apnea</subject><subject>Sleep Apnea, Obstructive - diagnosis</subject><subject>Sleep Breathing Physiology and Disorders • Original Article</subject><subject>Sleep disorders</subject><issn>1520-9512</issn><issn>1522-1709</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ALSLI</sourceid><sourceid>M2R</sourceid><recordid>eNp9kUtvFiEUhonR2Fr9Ay4MiRsXjnJggJll0_SW1HRRXRMGznwfzdwEprV_or-5tF_VxIULAofzvC-Xl5D3wL4AY_prAhBcVozzMmSjK3hB9kGWEjRrXz6tWdVK4HvkTUrXjEHdtPCa7AnJQbeC75P7418YXUhInV2sC_mORhxtmBJN64JxmuNoh880b-d1s6VjGPzwiPjVoadhKjveD1jZTSlLN2Qb72gRpnmacKC3IW_pt9ljtBlpnukV3mBEetmlHFeXww3SqwFxoYfLhPYtedXbIeG75_mA_Dg5_n50Vl1cnp4fHV5UTmiZK-VQNOC86LRwsq-9A6a1bpiTXdertrOAtZYN7xW2HVfQgdPl9dZbKaHm4oB82vkucf65YspmDMnhMNgJ5zUZroRoGVe8KejHf9DreY1TuZ3hjQIlFNSsUHxHuTinFLE3Swxj-QsDzDymZXZpmZKWeUrLQBF9eLZeuxH9H8nveAogdkAqrWmD8e_Z_7F9ALeCoac</recordid><startdate>20230301</startdate><enddate>20230301</enddate><creator>Arora, Subodh K.</creator><creator>Powell, Tyler A.</creator><creator>Foster, Shannon N.</creator><creator>Hansen, Shana L.</creator><creator>Morris, Michael J.</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7T5</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88J</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2R</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2850-8044</orcidid></search><sort><creationdate>20230301</creationdate><title>Exercise capacity remains supernormal, though mildly reduced in middle-aged military personnel with Moderate to Severe Obstructive Sleep Apnea</title><author>Arora, Subodh K. ; Powell, Tyler A. ; Foster, Shannon N. ; Hansen, Shana L. ; Morris, Michael J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-6ce381cd3b73c5f4dc1077780c5bbf69ba1e47582f6e9b261b1c7014ada551423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Aged</topic><topic>Apnea</topic><topic>Body weight</topic><topic>Dentistry</topic><topic>Exercise</topic><topic>Exercise Tolerance</topic><topic>Humans</topic><topic>Hypoxemia</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Maximum oxygen consumption</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle age</topic><topic>Middle Aged</topic><topic>Military Personnel</topic><topic>Neurology</topic><topic>Otorhinolaryngology</topic><topic>Overweight</topic><topic>Pediatrics</topic><topic>Pneumology/Respiratory System</topic><topic>Sleep apnea</topic><topic>Sleep Apnea, Obstructive - diagnosis</topic><topic>Sleep Breathing Physiology and Disorders • Original Article</topic><topic>Sleep disorders</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arora, Subodh K.</creatorcontrib><creatorcontrib>Powell, Tyler A.</creatorcontrib><creatorcontrib>Foster, Shannon N.</creatorcontrib><creatorcontrib>Hansen, Shana L.</creatorcontrib><creatorcontrib>Morris, Michael J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection【Remote access available】</collection><collection>ProQuest Central (Corporate)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Social Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Social Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Sleep & breathing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arora, Subodh K.</au><au>Powell, Tyler A.</au><au>Foster, Shannon N.</au><au>Hansen, Shana L.</au><au>Morris, Michael J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Exercise capacity remains supernormal, though mildly reduced in middle-aged military personnel with Moderate to Severe Obstructive Sleep Apnea</atitle><jtitle>Sleep & breathing</jtitle><stitle>Sleep Breath</stitle><addtitle>Sleep Breath</addtitle><date>2023-03-01</date><risdate>2023</risdate><volume>27</volume><issue>1</issue><spage>137</spage><epage>144</epage><pages>137-144</pages><issn>1520-9512</issn><eissn>1522-1709</eissn><abstract>Introduction
The relationship between moderate to severe OSA and exercise capacity remains unclear. Prior studies showing a reduction in VO
2
max in this population have mostly involved middle-aged, overweight patients. We aimed to study this relationship in a similarly aged population of military personnel with previously undiagnosed moderate to severe OSA.
Methods
We studied late-career male military personnel who underwent CPET and polysomnography (PSG). Patients were categorized either into an OSA group (apnea–hypopnea index (AHI) ≥ 15 events/h) or a control group (AHI < 15 events/h). VO
2
max was compared between groups.
Results
170 male military personnel met criteria for the study. Mean AHI was 29.0/h in the OSA group (
n
= 58) versus 7.4/h in the controls (
n
= 112) while SpO
2
nadir was slightly lower (86.0% vs. 89.0%). Patients were of similar age (53.1 vs. 53.7 years), and BMI was slightly higher in the OSA group (27.5 kg/m
2
vs. 26.3 kg/m
2
). Percent-predicted VO
2
max was supernormal in both groups, though it was comparatively lower in the OSA group (117% vs. 125%;
p
< 0.001).
Conclusions
Military personnel with moderate to severe OSA were able to achieve supernormal VO
2
max values, yet had an 8% decrement in exercise capacity compared to controls. These findings suggest that OSA without significant hypoxemia may not significantly influence exercise capacity. It remains likely that the effects of untreated OSA on exercise capacity are complex and are affected by several variables including BMI, degree of associated hypoxemia, and regularity of exercise. Statistically lower VO
2
max noted in this study may suggest that untreated OSA in less fit populations may lead to significant decrements in exercise capacity.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>35217932</pmid><doi>10.1007/s11325-022-02587-1</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-2850-8044</orcidid></addata></record> |
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| ispartof | Sleep & breathing, 2023-03, Vol.27 (1), p.137-144 |
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| source | Social Science Premium Collection; Springer Link |
| subjects | Aged Apnea Body weight Dentistry Exercise Exercise Tolerance Humans Hypoxemia Internal Medicine Male Maximum oxygen consumption Medicine Medicine & Public Health Middle age Middle Aged Military Personnel Neurology Otorhinolaryngology Overweight Pediatrics Pneumology/Respiratory System Sleep apnea Sleep Apnea, Obstructive - diagnosis Sleep Breathing Physiology and Disorders • Original Article Sleep disorders |
| title | Exercise capacity remains supernormal, though mildly reduced in middle-aged military personnel with Moderate to Severe Obstructive Sleep Apnea |
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