A new view of how cytoplasmic viscosity affects microtubule dynamics

How the physical nature of the cytoplasm shapes cellular processes has been increasingly studied in recent years. Work in this issue demonstrates that cytoplasmic viscosity affects the dynamic instability of microtubules. Surprisingly, both polymerization and depolymerization slow with increasing vi...

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Bibliographic Details
Published in:Developmental cell 2022-02, Vol.57 (4), p.419-420
Main Author: Betterton, Meredith D.
Format: Article
Language:English
Subjects:
Cytoplasm
Cytosol
Microtubules
Polymerization
Viscosity
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Summary:How the physical nature of the cytoplasm shapes cellular processes has been increasingly studied in recent years. Work in this issue demonstrates that cytoplasmic viscosity affects the dynamic instability of microtubules. Surprisingly, both polymerization and depolymerization slow with increasing viscosity. This raises interesting questions for future work. How the physical nature of the cytoplasm shapes cellular processes has been increasingly studied in recent years. Work in this issue demonstrates that cytoplasmic viscosity affects the dynamic instability of microtubules. Surprisingly, both polymerization and depolymerization slow with increasing viscosity. This raises interesting questions for future work.
ISSN:1534-5807
1878-1551
1878-1551
DOI:10.1016/j.devcel.2022.02.006