Early high protein provision and mortality in ICU patients including those receiving continuous renal replacement therapy

Background Findings on the association between early high protein provision and mortality in ICU patients are inconsistent. The relation between early high protein provision and mortality in patients receiving CRRT remains unclear. The aim was to study the association between early high protein prov...

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Bibliographic Details
Published in:European journal of clinical nutrition 2022-09, Vol.76 (9), p.1303-1308
Main Authors: van Ruijven, Isabel M., Stapel, Sandra N., Girbes, Armand R. J., Weijs, Peter J. M.
Format: Article
Language:English
Subjects:
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692/699
Clinical Nutrition
Epidemiology
Internal Medicine
Medicine
Medicine & Public Health
Metabolic Diseases
Mortality
Patients
Proteins
Public Health
Sensitivity analysis
Subgroups
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Summary:Background Findings on the association between early high protein provision and mortality in ICU patients are inconsistent. The relation between early high protein provision and mortality in patients receiving CRRT remains unclear. The aim was to study the association between early high protein provision and hospital and ICU mortality and consistency in subgroups. Methods A retrospective cohort study was conducted in 2618 ICU patients with a feeding tube and mechanically ventilated ≥48 h (2003–2016). The association between early high protein provision (≥1.2 g/kg/day at day 4 vs.
ISSN:0954-3007
1476-5640
DOI:10.1038/s41430-022-01103-8