Efficacy and Safety of Topical Solution of Diperoxochloric Acid for Neuropathic Diabetic Foot Ulcer: Results from a Phase 3, Multicentre, Randomized, Active-controlled, Parallel-group Study

Diabetic foot ulcer (DFU), if untreated, accounts for lower-limb amputations affecting patients’ quality-of-life. Diperoxochloric acid (DPOCL) is known to heal DFU by its antibacterial and fibroblast stimulating activity. This was a phase 3, multicentre, randomized, double-blind, active-controlled,...

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Bibliographic Details
Published in:International journal of lower extremity wounds 2024-12, Vol.23 (4), p.551-559
Main Authors: Bal, Arun, Jain, Sudhir Kumar, Jagannath, Mohapatra, Kailash Chandra, Rao, Shilpa, Deshpande, Neeta, Munshi, Renuka, Mahey, Rajeshkumar, Chowdhury, Subhankar, Bhaskar, M.M., Singh, Sapam Opendro, Damle, Gauri, Damir, Ashok, Phal, Smita, Zarapkar, Mukund
Format: Article
Language:English
Subjects:
Administration, Topical
Adult
Aged
Diabetic Foot - drug therapy
Double-Blind Method
Female
Humans
Male
Middle Aged
Treatment Outcome
Wound Healing - drug effects
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Summary:Diabetic foot ulcer (DFU), if untreated, accounts for lower-limb amputations affecting patients’ quality-of-life. Diperoxochloric acid (DPOCL) is known to heal DFU by its antibacterial and fibroblast stimulating activity. This was a phase 3, multicentre, randomized, double-blind, active-controlled, parallel-group study conducted to evaluate the efficacy and safety of topic solution of DPOCL compared with isotonic sodium chloride solution (ISCL). Adult patients with type 1 or 2 diabetes with random blood glucose levels of
ISSN:1534-7346
1552-6941
1552-6941
DOI:10.1177/15347346221076625