Outcomes of surgical versus non-surgical treatment of resectable T4a laryngeal and hypopharyngeal carcinoma

ObjectiveSurgery is the recommended treatment for resectable T4a laryngeal and hypopharyngeal carcinoma. Non-surgical treatment is an option in a select few patients.MethodThis retrospective study was undertaken to assess the treatment outcomes in patients with resectable T4a carcinoma of the larynx...

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Bibliographic Details
Published in:Journal of laryngology and otology 2022-11, Vol.136 (11), p.1087-1095
Main Authors: Thiagarajan, S, Gupta, M, Sathe, P, Gill, G, Ghosh-Laskar, S, Prabhash, K, Chaukar, D
Format: Article
Language:English
Subjects:
Cancer therapies
Cartilage
Chemotherapy
Disease
Electronic health records
Hypopharynx
Laryngeal cancer
Larynx
Lymphatic system
Main Article
Medical records
Oncology
Ostomy
Patients
Radiation therapy
Statistical analysis
Surgery
Survival
Survival analysis
Throat cancer
Thyroid gland
Tomography
Tracheotomy
Veterans
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Summary:ObjectiveSurgery is the recommended treatment for resectable T4a laryngeal and hypopharyngeal carcinoma. Non-surgical treatment is an option in a select few patients.MethodThis retrospective study was undertaken to assess the treatment outcomes in patients with resectable T4a carcinoma of the larynx and hypopharynx who received either surgical or non-surgical treatment at our institute and to assess factors influencing these outcomes.ResultsA total of 120 patients were included in the study. They were divided into groups A, B and C based on the presence of extralaryngeal spread through laryngeal membrane, cartilage or both. The overall survival was better among patients who received surgery than those who received non-surgical treatment in the three groups. The factor influencing overall survival was the treatment given in the form of surgical versus non-surgical treatment.ConclusionSurgery is the preferred treatment for T4a laryngeal and hypopharyngeal carcinoma, even in patients with extralaryngeal spread without cartilage erosion.
ISSN:0022-2151
1748-5460
DOI:10.1017/S0022215121004461