Potential toxicity of nickel nano and microparticles on the reproductive system of female rats: A comparative time-dependent study

Increased application of engineered nanoparticles in different sectors viz. agriculture, commerce, industry, and medicine has raised serious public health issues. Nanoparticles of nickel have been increasingly used as catalysts, conductive pastes, adhesives, nanowires, and nanofilters. Human and ani...

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Bibliographic Details
Published in:Toxicology and industrial health 2022-04, Vol.38 (4), p.234-247
Main Authors: Singh, Meenu, Verma, Yeshvandra, Rana, Suresh VS
Format: Article
Language:English
Subjects:
Agricultural engineering
Animals
Apoptosis
Bioaccumulation
Body weight
Catalysts
Cytotoxicity
Exposure
Female
Females
Hormones
Kidneys
Lipid Peroxidation
Lipids
Microparticles
Nanoparticles
Nanoparticles - toxicity
Nanotechnology
Nanowires
Nickel
Nickel - toxicity
Organs
Ovaries
Ovary
Oxidative Stress
Pastes
Peroxidation
Public health
Rats
Rats, Wistar
Reactive oxygen species
Reproductive system
Rodents
Steroid hormones
Steroidogenesis
Time dependence
Toxicity
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Summary:Increased application of engineered nanoparticles in different sectors viz. agriculture, commerce, industry, and medicine has raised serious public health issues. Nanoparticles of nickel have been increasingly used as catalysts, conductive pastes, adhesives, nanowires, and nanofilters. Human and animal exposure to these particles may cause toxicity in different organs/systems. Studies made in the past had demonstrated their toxicity in liver, kidney, and lungs. However, their reproductive effects remain poorly understood. Therefore, the present study on reproductive toxicity of nickel nanoparticles (
ISSN:0748-2337
1477-0393
DOI:10.1177/07482337221074762