Effect of quadrant switch on ıntraocular pressure change in ıntravitreal aflibercept or ranibizumab ınjection applications

Objective To evaluate the effect of injection quadrant switch on the intraocular pressure (IOP) change in intravitreal aflibercept or ranibizumab applications. Methods 123 eyes of 123 patients who received intravitreal injection (IVE) into the superotemporal quadrant at least 10 times for age-relate...

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Bibliographic Details
Published in:International ophthalmology 2022-09, Vol.42 (9), p.2841-2846
Main Authors: Altintas, Melek, Ulas, Fatih, Celebi, Serdal, Uyar, Enes
Format: Article
Language:English
Subjects:
Age
Age related diseases
Diabetes
Diabetes mellitus
Edema
Eye diseases
Injection
Intraocular pressure
Iodine
Macular degeneration
Medicine
Medicine & Public Health
Monoclonal antibodies
Ophthalmology
Original Paper
Patients
Quadrants
Statistical analysis
Surgery
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Summary:Objective To evaluate the effect of injection quadrant switch on the intraocular pressure (IOP) change in intravitreal aflibercept or ranibizumab applications. Methods 123 eyes of 123 patients who received intravitreal injection (IVE) into the superotemporal quadrant at least 10 times for age-related macular degeneration or diabetic macular edema have been recruited. The demographic data, lens status, IOP values (preoperative, postoperative 0th min, and postoperative 30th min), and amount of vitreous reflux (VR) following IVE have been recorded. Next IVE application was performed into the inferotemporal quadrant of the patient, which had never been injected before. Results The mean IOP value at postoperative 0th min was 50.24 ± 7.66 mmHg after injections into the superotemporal quadrant and was 34.85 ± 4.96 mmHg after injections into the inferotemporal quadrant. No significant difference was observed between the preoperative and postoperative 30th min-IOP values ( p  > 0.05), while a significant difference was found between the postoperative 0th min-IOP values among quadrants ( p  
ISSN:1573-2630
0165-5701
1573-2630
DOI:10.1007/s10792-022-02274-w