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Primary adrenal mature teratoma: A rare case report and review of literature

IntroductionTeratoma is a germ cell tumor, deriving from totipotent cells. Teratomas usually occur in gonads and are rarely extra-gonadal. The adrenal location is exceptional. Only few cases of primary adrenal teratomas have been reported in literature, mainly in young patients. Case reportWe report...

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Published in:Annals of medicine and surgery (2012) 2022, Vol.75, p.103422-103422
Main Authors: Assarrar, Imane, Harhar, Marouane, Zerrouki, Dounia, Draoui, Najat, Miry, Achraf, Bennani, Amal, Rouf, Siham, El Harroudi, Tijani, Latrech, Hanane
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container_title Annals of medicine and surgery (2012)
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creator Assarrar, Imane
Harhar, Marouane
Zerrouki, Dounia
Draoui, Najat
Miry, Achraf
Bennani, Amal
Rouf, Siham
El Harroudi, Tijani
Latrech, Hanane
description IntroductionTeratoma is a germ cell tumor, deriving from totipotent cells. Teratomas usually occur in gonads and are rarely extra-gonadal. The adrenal location is exceptional. Only few cases of primary adrenal teratomas have been reported in literature, mainly in young patients. Case reportWe report the case of a 56-year-old female patient who presented with pyrosis, dyspepsia and abdominal pain that was evolving for 5 months. The abdominal computed tomography revealed a voluminous mass of the right adrenal gland and the hormonal evaluation was normal. The patient underwent an open transperitoneal adrenalectomy and the histopathological examination of the specimen confirmed the diagnosis of mature teratoma. DiscussionAdrenal teratomas are commonly asymptomatic and their diagnosis depends mostly on radiologic findings. Malignant transformation is very rare. Surgical excision is the mainstay of treatment with a good prognosis. ConclusionOpen surgery should always be considered in large and adhering teratoma tumors of the adrenal gland. Some pathologic features and tumorigenesis of adrenal teratomas are not entirely elucidated, thus the importance of larger studies in order to comprehend this pathological entity.
doi_str_mv 10.1016/j.amsu.2022.103422
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Teratomas usually occur in gonads and are rarely extra-gonadal. The adrenal location is exceptional. Only few cases of primary adrenal teratomas have been reported in literature, mainly in young patients. Case reportWe report the case of a 56-year-old female patient who presented with pyrosis, dyspepsia and abdominal pain that was evolving for 5 months. The abdominal computed tomography revealed a voluminous mass of the right adrenal gland and the hormonal evaluation was normal. The patient underwent an open transperitoneal adrenalectomy and the histopathological examination of the specimen confirmed the diagnosis of mature teratoma. DiscussionAdrenal teratomas are commonly asymptomatic and their diagnosis depends mostly on radiologic findings. Malignant transformation is very rare. Surgical excision is the mainstay of treatment with a good prognosis. ConclusionOpen surgery should always be considered in large and adhering teratoma tumors of the adrenal gland. Some pathologic features and tumorigenesis of adrenal teratomas are not entirely elucidated, thus the importance of larger studies in order to comprehend this pathological entity.</description><identifier>ISSN: 2049-0801</identifier><identifier>EISSN: 2049-0801</identifier><identifier>DOI: 10.1016/j.amsu.2022.103422</identifier><language>eng</language><ispartof>Annals of medicine and surgery (2012), 2022, Vol.75, p.103422-103422</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>780,784,4489,27924</link.rule.ids></links><search><creatorcontrib>Assarrar, Imane</creatorcontrib><creatorcontrib>Harhar, Marouane</creatorcontrib><creatorcontrib>Zerrouki, Dounia</creatorcontrib><creatorcontrib>Draoui, Najat</creatorcontrib><creatorcontrib>Miry, Achraf</creatorcontrib><creatorcontrib>Bennani, Amal</creatorcontrib><creatorcontrib>Rouf, Siham</creatorcontrib><creatorcontrib>El Harroudi, Tijani</creatorcontrib><creatorcontrib>Latrech, Hanane</creatorcontrib><title>Primary adrenal mature teratoma: A rare case report and review of literature</title><title>Annals of medicine and surgery (2012)</title><description>IntroductionTeratoma is a germ cell tumor, deriving from totipotent cells. 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title Primary adrenal mature teratoma: A rare case report and review of literature
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