Performance of timed function tests as outcome measures in idiopathic inflammatory myopathy-results from a single-centre cohort

To evaluate performance of timed function tests (TFTs) in assessing muscle strength and endurance as determined by Manual Muscle Testing 8 (MMT-8) and Functional Index 2 (FI-2), respectively, in idiopathic inflammatory myopathies (IIM). This cohort study included 42 IIM patients satisfying 2017 EULA...

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Published in:Rheumatology (Oxford, England) England), 2022-12, Vol.62 (1), p.290-299
Main Authors: Dunga, Saikumar, Kavadichanda, Chengappa, Bairwa, Devender, Thabah, Molly Mary, Negi, Vir Singh
Format: Article
Language:English
Subjects:
Cohort Studies
Humans
Muscle Strength
Myositis - diagnosis
Outcome Assessment, Health Care
Patient Reported Outcome Measures
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Summary:To evaluate performance of timed function tests (TFTs) in assessing muscle strength and endurance as determined by Manual Muscle Testing 8 (MMT-8) and Functional Index 2 (FI-2), respectively, in idiopathic inflammatory myopathies (IIM). This cohort study included 42 IIM patients satisfying 2017 EULAR/ACR criteria. Patients were classified as active (n = 18) or inactive disease (n = 24) based on clinical status at baseline. MMT-8, FI-2, 30 s rise from chair test, 30 s 1 kg arm rise test and 2-min walking distance (2MWD) were administered at baseline, 3 months and 6 months. Pearson rank correlation analysis and receiver operating curves were performed to assess the performance of timed function tests. All patients were followed up at 3 months and 39 completed 6 months' follow-up. All the three TFTs had excellent convergent (r > 0.7, P 
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/keac244